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Resatorvid

Resatorvid structure

CAS No:
243984-11-4
Formula:
C15H17ClFNO4S
Chemical Name:
Resatorvid
Synonyms:
1-Cyclohexene-1-carboxylic acid,6-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-,ethyl ester,(6R)-;TAK 242;Resatorvid
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Resatorvid is an investigational compound designed for the treatment of severe sepsis.

Resatorvid Basic Attributes

Molecular Weight：

361.81600

Exact Mass：

361.82

UNII：

H2MZ648C31

Characteristics

PSA：

80.85000

XLogP3：

4.41660

Density：

1.39g/cm3

Melting Point：

54-55 °C @ Solvent: Diisopropyl ether, Hexane

Boiling Point：

461.958ºC

Flash Point：

233.184ºC

Refractive Index：

1.574

Vapor Pressure：

0mmHg at 25°C

Drug Information

Drug Indication：

Investigated for use/treatment in sepsis and septicemia.

Mechanism of Action：

TAK-242 suppresses production of inflammatory mediators such as cytokine by inhibiting the signal transduction through Toll-like receptor 4 (TLR4) which is one of the receptors recognizing the bacterial components.

MeSH Entry Terms：

CLI 095

Computed Properties

Molecular Weight:361.8
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:361.0550851
Monoisotopic Mass:361.0550851
Topological Polar Surface Area:80.8
Heavy Atom Count:23
Complexity:560
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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Resatorvid

CAS No.: 243984-11-4

Content: 99.00%

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Hangzhou KieRay Chem Co.,LTD Contact Supplier

CN
5 YRS

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RESATORVID

CAS No.: 243984-11-4

Grade: industrial Grade

Content: 98%

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