 Home > Encyclopedia > 1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-, hydrochloride (1:1)

1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-, hydrochloride (1:1)

1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-, hydrochloride (1:1) structure

CAS No:
136-69-6
Formula:
C18H21NO5.ClH
Chemical Name:
1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-, hydrochloride (1:1)
Synonyms:
1,2-Benzenediol,4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-,hydrochloride (1:1);Benzyl alcohol,3,4-dihydroxy-α-[[[α-methyl-3,4-(methylenedioxy)phenethyl]amino]methyl]-,hydrochloride;1,2-Benzenediol,4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-,hydrochloride;Protocatechuyl alcohol,α-[[(α-methyl-3,4-methylenedioxyphenethyl)amino]methyl]-,hydrochloride;Caytine hydrochloride;Protokylol hydrochloride;NSC 113490

Request for Quotation

Description

Protokylol Hydrochloride is the hydrochloride salt form of protokylol, a derivative of the beta-adrenergic receptor agonist isoproterenol with bronchodilator activity. Protokylol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.

1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-, hydrochloride (1:1) Basic Attributes

Molecular Weight：

367.82400

Exact Mass：

367.1186505 g/mol

EC Number：

205-254-8

UNII：

7U7O8Q48IO

NSC Number：

113490

NCI Thesaurus Code：

C66496

Characteristics

PSA：

91.18000

XLogP3：

3.27360

Density：

1.336g/cm3

Melting Point：

126-127 °C

Boiling Point：

585ºC

Flash Point：

307.6ºC

Vapor Pressure：

1.57E-14mmHg at 25°C

Drug Information

MeSH Entry Terms：

alpha-(alpha-methyl-3,4-methylenedioxyphenethylamino)methyl protocatechuyl alcohol

1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-, hydrochloride (1:1) Use and Manufacturing

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:367.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:367.1186505
Monoisotopic Mass:367.1186505
Topological Polar Surface Area:91.2
Heavy Atom Count:25
Complexity:396
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Learn More Other Chemicals

Hot Searches: serpiginous; isobutyl alcohol; stroke lacunar infarct; hydroxide anion; dimethyl sulfone; h2s compound name

Guide of 1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-, hydrochloride (1:1)

Description
Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.