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8-oxo-dGTP

8-oxo-dGTP structure

8-oxo-dGTP 

structure
  • CAS No:

    139307-94-1

  • Formula:

    C10H16N5O14P3

  • Chemical Name:

    8-oxo-dGTP

  • Synonyms:

    2,2,7,7-Tetramethyltricyclo<6.2.1.03.8>-undecan-4-on; 2'-Deoxy-8-oxo-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphat e); 2'-deoxy-7,8-dihydro-8-oxoguanosine-5'-triphosphate; ETHYL 4-METHYL-2-OXO-6-[(Z)-2-PHENYLETHENYL]-3,6-DIHYDRO-1H-PYRIMIDINE-5-CARBOXYLATE; 6-methyl-5-phenyl-imidazo[5,1-c][1,4]oxazin-8-one; 8-oxo-2'-deoxyguanosine 5'-triphosphate; 8-oxo-7,8-dihydro-2'-deoxyguanosine triphosphate; 8-Oxo-6-methyl-5-phenyl-8H-imidazo-<5.1-c><1.4>oxazin;Expand

Description

8-oxo-dGTP is a purine 2'-deoxyribonucleoside 5'-triphosphate having 8-oxo-7,8-dihydroguanine as the nucleobase. It has a role as a mutagen. It is a conjugate acid of an 8-oxo-dGTP(3-).

8-oxo-dGTP Basic Attributes

523.18000

522.99066119

Characteristics

329.52000

-1.25850

2.75g/cm3

1.935

Drug Information

Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. (See all compounds classified as Mutagens.)

8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate

Computed Properties

Molecular Weight:523.18
XLogP3:-6.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:8
Exact Mass:522.99066119
Monoisotopic Mass:522.99066119
Topological Polar Surface Area:289
Heavy Atom Count:32
Complexity:1040
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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