N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-3-oxo-1H-isoindole-2-carboxamide
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![N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-3-oxo-1H-isoindole-2-carboxamide structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/1c1707aecb8c4c87bd945eadb8f442ad.png "N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-3-oxo-1H-isoindole-2-carboxamide")
N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-3-oxo-1H-isoindole-2-carboxamide
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CAS No:
71010-45-2
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Formula:
C24H28N4O5S
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Chemical Name:
N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-3-oxo-1H-isoindole-2-carboxamide
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Synonyms:
N-(4-[2-(1-oxo-isoindoline-2-carboxamido)-ethyl]benzenesulfonyl)-N'-cyclohexyl-urea; UNII-1928X5O3S5; 1-Cyclohexyl-3-((p-(2-(1-oxo-2-isoindolinecarboxamido)ethyl)phenyl)sulfonyl)urea; Glisindamide; Glisindamide [INN];
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CAS No:
Description
Glisindamide is a second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, glisindamide exerts greater binding affinity to sulfonylurea receptor type 1 (SUR1) than the first-generation compounds and shows peroxisome proliferator-activated receptor gamma (PPARgamma) agonistic activity.
N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-3-oxo-1H-isoindole-2-carboxamide Basic Attributes
484.56800
484.17804118
1928X5O3S5
DTXSID50221243
C74144
2935009090
Computed Properties
Molecular Weight:484.6
XLogP3:4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:484.17804118
Monoisotopic Mass:484.17804118
Topological Polar Surface Area:133
Heavy Atom Count:34
Complexity:844
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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