Lonazolac
-
Lonazolac
structure -
-
CAS No:
53808-88-1
-
Formula:
C17H13ClN2O2
-
Chemical Name:
Lonazolac
-
Synonyms:
1H-Pyrazole-4-acetic acid,3-(4-chlorophenyl)-1-phenyl-;3-(4-Chlorophenyl)-1-phenyl-1H-pyrazole-4-acetic acid;Lonazolac;3-(p-Chlorophenyl)-1-phenylpyrazole-4-acetic acid;3-(4-Chlorophenyl)-1-phenylpyrazole-4-acetic acid;2-[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]acetic acid;122729-35-5
-
CAS No:
Description
Lonazolac is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 3-(4-chlorophenyl)-1-phenylpyrazol-4-yl group. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and an antineoplastic agent. It is a monocarboxylic acid, a member of pyrazoles and a member of monochlorobenzenes. It derives from an acetic acid. It is a conjugate acid of a lonazolac(1-).
Lonazolac Basic Attributes
312.75000
312.75
258-791-5
13097143QI
319772
DTXSID4046151
M - Musculo-skeletal system
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
3-(4-chlorophenyl)-1-phenylpyrazole-4-acetic acid
Computed Properties
Molecular Weight:312.7
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:312.0665554
Monoisotopic Mass:312.0665554
Topological Polar Surface Area:55.1
Heavy Atom Count:22
Complexity:379
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Request for Quotation