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1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one

1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one structure

CAS No:
153587-01-0
Formula:
C15H8F6N2O2
Chemical Name:
1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one
Synonyms:
2H-Benzimidazol-2-one,1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-;1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one;NS 1619
Categories:
Organic Chemistry > Hydrazine or Hydroxylamine Derivatives

Description

NS 1619 is a member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca). It has a role as a potassium channel opener. It is a member of benzimidazoles, a member of phenols and a member of (trifluoromethyl)benzenes.

1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one Basic Attributes

Molecular Weight：

362.22700

Exact Mass：

362.23

DSSTox ID：

DTXSID80165363

HScode：

2933990090

Characteristics

PSA：

58.02000

XLogP3：

4.06200

Density：

1.563g/cm3

Refractive Index：

1.538

Drug Information

MeSH Entry Terms：

1-(2'-hydroxy-5'-trifluoromethylphenyl)-5-trifluoromethyl-2(3H)-benzimidazolone

Computed Properties

Molecular Weight:362.23
XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:1
Exact Mass:362.04899647
Monoisotopic Mass:362.04899647
Topological Polar Surface Area:52.6
Heavy Atom Count:25
Complexity:523
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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NS 1619

CAS No.: 153587-01-0

Content: 99.00%

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NS 1619 99% see COA Kanbei kanbei

CAS No.: 153587-01-0

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Guide of 1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one

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Basic Attributes
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