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Linopirdine

Linopirdine structure

Linopirdine 

structure
  • CAS No:

    105431-72-9

  • Formula:

    C26H21N3O

  • Chemical Name:

    Linopirdine

  • Synonyms:

    2H-Indol-2-one,1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-;1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one;DuP 996;Linopirdine;1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one

Description

Linopirdine is a member of indoles.

Linopirdine Basic Attributes

391.46400

391.46

I5TB3NZ94T

DTXSID6045163

N - Nervous system

2933790090

Characteristics

46.09000

4.94310

1.255g/cm3

186-186.5 °C

655.9ºC

350.5ºC

1.669

4.45E-17mmHg at 25°C

Drug Information

A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS. (See all compounds classified as Potassium Channel Blockers.)|Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. (See all compounds classified as Neuroprotective Agents.)

3,3-bis(4-pyridylmethyl)-1-phenylindolin-2-one

Computed Properties

Molecular Weight:391.5
XLogP3:4.1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:391.168462302
Monoisotopic Mass:391.168462302
Topological Polar Surface Area:46.1
Heavy Atom Count:30
Complexity:555
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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