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Home > Encyclopedia > 7-[3-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]propoxy]-3,4-dimethylchromen-2-one

7-[3-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]propoxy]-3,4-dimethylchromen-2-one

7-[3-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]propoxy]-3,4-dimethylchromen-2-one structure

7-[3-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]propoxy]-3,4-dimethylchromen-2-one 

structure
  • CAS No:

    39577-19-0

  • Formula:

    C25H29ClN2O3

  • Chemical Name:

    7-[3-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]propoxy]-3,4-dimethylchromen-2-one

  • Synonyms:

    7-{3-[4-(4-chloro-benzyl)-piperazin-1-yl]-propoxy}-3,4-dimethyl-chromen-2-one; 7-(3-(4-(p-Chlorobenzyl)-1-piperazinyl)propoxy)-3,4-dimethylcoumarin; Picumast [BAN:INN]; Picumast; C25H29ClN2O3;

7-[3-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]propoxy]-3,4-dimethylchromen-2-one Basic Attributes

440.96200

440.1866705 g/mol

125267OAUF

DTXSID20192693

2934999090

Characteristics

45.92000

4.52570

1.208g/cm3

594.8ºC

313.5ºC

1.587

Drug Information

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)

3,4-dimethyl-7-(4-(p-chlorobenzyl)piperazin-1-yl)propoxycoumarin.di-HCl

Computed Properties

Molecular Weight:441.0
XLogP3:4.5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:440.1866705
Monoisotopic Mass:440.1866705
Topological Polar Surface Area:42
Heavy Atom Count:31
Complexity:639
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Guide of 7-[3-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]propoxy]-3,4-dimethylchromen-2-one

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