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Farglitazar

Farglitazar structure

CAS No:
196808-45-4
Formula:
C34H30N2O5
Chemical Name:
Farglitazar
Synonyms:
L-Tyrosine,N-(2-benzoylphenyl)-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-;N-(2-Benzoylphenyl)-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-L-tyrosine;Farglitazar;GI 262570X;GI 262570;G1 262570;274687-78-4

Description

Farglitazar is an L-tyrosine derived and peroxisome proliferator-activated receptor (PPAR) agonist with hypoglycemic and lipid lowering activity. Farglitazar shows greater selectivity over PPARgamma than PPARalpha. This agent is developed for the treatment of hepatic fibrosis.

Farglitazar Basic Attributes

Molecular Weight：

546.61200

Exact Mass：

546.61

UNII：

3433GY7132

DSSTox ID：

DTXSID1047310

NCI Thesaurus Code：

C81693

Characteristics

PSA：

101.66000

XLogP3：

6.68330

Melting Point：

148-150 °C

Boiling Point：

793.7ºC

Flash Point：

433.8ºC

Refractive Index：

1.639

Vapor Pressure：

1.45E-26mmHg at 25°C

Drug Information

MeSH Entry Terms：

farglitazar

Computed Properties

Molecular Weight:546.6
XLogP3:7.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:12
Exact Mass:546.21547206
Monoisotopic Mass:546.21547206
Topological Polar Surface Area:102
Heavy Atom Count:41
Complexity:818
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of Farglitazar

Description
Basic Attributes
Characteristics
Drug Information
Computed Properties

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