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Home > Encyclopedia > N-Succinimidyl 3-(2-pyridyldithio)propionate

N-Succinimidyl 3-(2-pyridyldithio)propionate

N-Succinimidyl 3-(2-pyridyldithio)propionate structure

N-Succinimidyl 3-(2-pyridyldithio)propionate 

structure
  • CAS No:

    68181-17-9

  • Formula:

    C12H12N2O4S2

  • Chemical Name:

    N-Succinimidyl 3-(2-pyridyldithio)propionate

  • Synonyms:

    Propanoic acid,3-(2-pyridinyldithio)-,2,5-dioxo-1-pyrrolidinyl ester;2,5-Pyrrolidinedione,1-[1-oxo-3-(2-pyridinyldithio)propoxy]-;N-Succinimidyl 3-(2-pyridyldithio)propionate;SPDP;N-Hydroxysuccinimidyl 3-(2-pyridyldithio)propionate;3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester;NSC 344485;NSC 677449;Succinimidyl 3-[[(2-pyridyl)thio]thio]propionate;SPDP-OSu;N-Succinimidyl 3-(pyridyldithio)propionate;(2,5-Dioxopyrrolidin-1-yl) 3-(pyridin-2-yldisulfanyl)propanoate;Succinimidyl 3-[(2-pyridyl)dithio]propionate

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

N-Succinimidyl 3-(2-pyridyldithio)propionate Basic Attributes

312.36500

312.36

269-034-3

2OHG8V08NL

677449|344485

DTXSID60218366

Characteristics

127.17000

1.75710

White Solid

1.48 g/cm3

84-86ºC(lit.)

465.9ºC at 760 mmHg

235.5ºC

1.649

-20ºC

Safety Information

3

R36/37/38

S26-S36

Xi

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 42 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other. (See all compounds classified as Cross-Linking Reagents.)

N-succinilimidyl 3-(2-pyridylthio)propionate

Computed Properties

Molecular Weight:312.4
XLogP3:0.7
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:312.02384922
Monoisotopic Mass:312.02384922
Topological Polar Surface Area:127
Heavy Atom Count:20
Complexity:376
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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