Voriconazole (2R,3R)-Isomer
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Voriconazole (2R,3R)-Isomer
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CAS No:
137234-76-5
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Formula:
C16H13ClF3N5O
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Chemical Name:
Voriconazole (2R,3R)-Isomer
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Synonyms:
Voriconazole (2R,3R)-Isomer;(2R,3R)-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol compound with (2S,3S)-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1- (1H-1,2,4-triazol-1-yl)butan-2-ol (1:1);(αR,βR)-rel-6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol;4-Pyrimidineethanol, 6-chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βR)-rel-;Voriconazole 3-Epimer;(αR,?βR)?-?rel-6-?Chloro-?α-?(2,?4-?difluorophenyl)?-?5-?fluoro-?β-?methyl-?α-?(1H-?1,?2,?4-?triazol-?1-?ylmethyl)?-4-?pyrimidineethanol;(2R,3R)-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol compound with (2S,3S);Azilsartan medoxomil impurity317
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CAS No:
Characteristics
76.7 Ų
1.51±0.1 g/cm3(Predicted)
529.9±60.0 °C(Predicted)
11.44±0.29(Predicted)
-20°C Freezer
Voriconazole (2R,3R)-Isomer Use and Manufacturing
(αR,?βR)?-?rel-6-?Chloro-?α-?(2,?4-?difluorophenyl)?-?5-?fluoro-?β-?methyl-?α-?(1H-?1,?2,?4-?triazol-?1-?ylmethyl)?-4-?pyrimidineethanol is an intermediate in synthesizing rel-(R,R)-Voriconazole (V759990), The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor.
Computed Properties
Molecular Weight:420.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:419.0527500
Monoisotopic Mass:419.0527500
Topological Polar Surface Area:76.7
Heavy Atom Count:27
Complexity:481
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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