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Home > Encyclopedia > N,N-Dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium

N,N-Dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium

N,N-Dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium structure

N,N-Dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium 

structure
  • CAS No:

    13900-14-6

  • Formula:

    C22H40NO

  • Chemical Name:

    N,N-Dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium

  • Synonyms:

    1-Dodecanaminium,N,N-dimethyl-N-(2-phenoxyethyl)-;Ammonium,dodecyldimethyl(2-phenoxyethyl)-;N,N-Dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium;Domiphen

Description

Domiphen is an aromatic ether.|Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.

N,N-Dimethyl-N-(2-phenoxyethyl)-1-dodecanaminium Basic Attributes

334.6 g/mol

334.310989899 g/mol

4AZL56CU0F

DTXSID2048080

A - Alimentary tract and metabolism

Characteristics

9.2 Ų

129-130 °C

Drug Information

Anti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions.

The efficacy and tolerability of domiphen bromide (domifen bromide), administered at a dosage of 0.5 mg every 4-6 hr in a double-blind placebo controlled study in 31 patients affected by acute infectious dental diseases, are described. After 2 days of treatment with the drug, there was a significant decrease in pain and inflammation. The drug elicited a good response, improved prognosis and reduced the number of days of illness.

Domiphen bromide is a quaternary antiseptic with actions and uses similar to those of cationic surfactants.

domiphen

Computed Properties

Molecular Weight:334.6
XLogP3:7.5
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:15
Exact Mass:334.310989899
Monoisotopic Mass:334.310989899
Topological Polar Surface Area:9.2
Heavy Atom Count:24
Formal Charge:1
Complexity:271
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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