Linsidomine
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Linsidomine
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CAS No:
33876-97-0
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Formula:
C6H10N4O2
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Chemical Name:
Linsidomine
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Synonyms:
1,2,3-Oxadiazolium,5-amino-3-(4-morpholinyl)-,inner salt;Sydnone imine,3-morpholino-;Sydnone imine,3-(4-morpholinyl)-;3-Morpholinosydnonimine;SIN 1;Linsidomine;Sydnonimine-1
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CAS No:
Drug Information
A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81) (See all compounds classified as Nitric Oxide Donors.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)|Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)|Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)
3-morpholino-sydnonimine
Computed Properties
Molecular Weight:170.17
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:170.08037557
Monoisotopic Mass:170.08037557
Topological Polar Surface Area:49.6
Heavy Atom Count:12
Complexity:222
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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