N-Nitrosomethylethylamine

88.11 g/mol

88.11

00RLM29Y3A

DTXSID6021036

Yellow liquid

32.7 Ų

0.04 (LogP)|log Kow = 0.04

0.9448 g/cm³ @ Temp: 18 °C

163 °C @ Press: 747 Torr

76°C

3.40 M|Soluble in water (30%) and in organic solvents & lipids

PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired. ... Facilities for dispensing ... should be contiguous to storage area. /Chemical carcinogens/

1.1 mm Hg at 20 °C (est)

0.945

Henry's Law constant = 1.44X10-6 atm-cu m/mol at 20 °C (est)

Hydroxyl radical reaction rate constant = 1.0X10-11 cu cm/molecule-sec at 25 °C (est)

Stable at room temperature for more than 14 days in neutral or alkaline aqueous solutions in dark; slightly less stable in acidic solutions; light sensitive, especally to ultraviolet light.|SLIGHTLY LESS STABLE IN ACIDIC SOLN; LIGHT SENSITIVE, ESPECIALLY TO ULTRA-VIOLET LIGHT

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.|SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.|PRECAUTIONS FOR "CARCINOGENS": There is no universal method of disposal that has been proved satisfactory for all carcinogenic compounds & specific methods of chem destruction ... published have not been tested on all kinds of carcinogen-containing waste. ... Summary of avail methods & recommendations ... must be treated as guide only. /Chemical carcinogens/|PRECAUTIONS FOR "CARCINOGENS": Total destruction ... by incineration may be only feasable method for disposal of contaminated laboratory waste from biological expt. However, not all incinerators are suitable. ... Most efficient type ... is probably the gas-fired type, in which a first-stage combustion with a less than stoichiometric air:fuel ratio is followed by a second stage with excess air. Some ... are designed to accept ... aqueous & organic-solvent solutions, otherwise it is necessary ... to absorb soln onto suitable combustible material, such as sawdust. Alternatively, chem destruction may be used, esp when small quantities ... are to be destroyed in laboratory. /Chemical carcinogens/|For more Disposal Methods (Complete) data for N-NITROSOMETHYLETHYLAMINE (7 total), please visit the HSDB record page.

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P201, P202, P261, P264, P270, P271, P280, P281, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 47 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H301: Toxic if swallowed [Danger Acute toxicity, oral]|P201, P202, P264, P270, P281, P301+P310, P308+P313, P321, P330, P405, and P501

Wear nitrile rubber gloves, protective laboratory coat, self-contained breathing apparatus, eye protection and protective shoes. /Nitrosamines/|PRECAUTIONS FOR "CARCINOGENS": ... Dispensers of liq detergent ... Safety pipettes ... for all pipetting. ... In animal laboratory ... protective suits (preferably disposable, one-piece & close-fitting at ankles & wrists), gloves, hair covering & overshoes. ... In chemical laboratory, gloves & gowns should always be worn ... however, gloves should not be assumed to provide full protection. Carefully fitted masks or respirators ... when working with particulates or gases, & disposable plastic aprons ... gowns ... /should be/ of distinctive color. /Chemical carcinogens/

Cover spill with a 1:1:1 mixture by weight of sodium carbonate or calcium carbonate, clay cat litter (bentonite) and sand. Scoop the mixture into an appropriately labeled container for disposal by burning. ... Dissolve the compound in a flammable solvent and spray into furnace with afterburner and scrubber. /Nitrosamines/|PRECAUTIONS FOR "CARCINOGENS": A high-efficiency particulate arrestor (HEPA) or charcoal filters can be used to minimize amt of carcinogen in exhausted air ventilated safety cabinets, lab hoods, glove boxes or animal rooms. ... Filter housing that is designed so that used filters can be transferred into plastic bag without contaminating maintenance staff is avail commercially. Filters should be placed in plastic bags immediately after removal. ... The plastic bag should be sealed immediately. ... The sealed bag should be labelled properly. ... Waste liquids ... should be placed or collected in proper containers for disposal. The lid should be secured & the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface ... is not contaminated. ... The plastic bag should also be sealed & labelled. ... Broken glassware ... should be decontaminated by solvent extraction, by chemical destruction, or in specially designed incinerators. /Chemical carcinogens/

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.|/If/ on skin, wash with strong soap solution immediately. Rinse well. /Nitrosamines/|Contaminated gloves, clothing, shoes /should be removed and cleaned/ at once or /destroyed/ by burning. /Nitrosamines/|PRECAUTIONS FOR "CARCINOGENS": Smoking, drinking, eating, storage of food or of food & beverage containers or utensils, & the application of cosmetics should be prohibited in any laboratory. All personnel should remove gloves, if worn, after completion of procedures in which carcinogens have been used. They should ... wash ... hands, preferably using dispensers of liq detergent, & rinse ... thoroughly. Consideration should be given to appropriate methods for cleaning the skin, depending on nature of the contaminant. No standard procedure can be recommended, but the use of organic solvents should be avoided. Safety pipettes should be used for all pipetting. /Chemical carcinogens/|For more Preventive Measures (Complete) data for N-NITROSOMETHYLETHYLAMINE (12 total), please visit the HSDB record page.

PRECAUTIONS FOR "CARCINOGENS": Procurement ... of unduly large amt ... should be avoided. To avoid spilling, carcinogens should be transported in securely sealed glass bottles or ampoules, which should themselves be placed inside strong screw-cap or snap-top container that will not open when dropped & will resist attack from the carcinogen. Both bottle & the outside container should be appropriately labelled. ... National post offices, railway companies, road haulage companies & airlines have regulations governing transport of hazardous materials. These authorities should be consulted before ... material is shipped. /Chemical Carcinogens/|PRECAUTIONS FOR "CARCINOGENS": When no regulations exist, the following procedure must be adopted. The carcinogen should be enclosed in a securely sealed, watertight container (primary container), which should be enclosed in a second, unbreakable, leakproof container that will withstand chem attack from the carcinogen (secondary container). The space between primary & secondary container should be filled with absorbent material, which would withstand chem attack from the carcinogen & is sufficient to absorb the entire contents of the primary container in the event of breakage or leakage. Each secondary container should then be enclosed in a strong outer box. The space between the secondary container & the outer box should be filled with an appropriate quantity of shock-absorbent material. Sender should use fastest & most secure form of transport & notify recipient of its departure. If parcel is not received when expected, carrier should be informed so that immediate effort can be made to find it. Traffic schedules should be consulted to avoid ... arrival on weekend or holiday ... /Chemical Carcinogens/

N-Nitrosomethylethylamine levels of 0.4 to 8 ug/cigarette have been detected in mainstream tobacco smoke from cigarettes and small cigars(1); levels of 9 to 30 ug/cigarette have been detected in sidestream tobacco smoke(1); levels of 75 ug/cigarette have been detected in sidestream smoke of small cigars(1). N-Nitrosomethylethylamine concns of 1 to 40 ng/cigarette were detected in smoke condensate from various cigarettes and cigars(2). N-Nitrosomethylethylamine levels of 3.9-41.2 ng/cigarette were detected in the mainstream smoke of 20 commercial brands of filter and non-filter cigarettes(3); levels were much lower in the cigarette tobacco(3).

LD50 BD Rat 90 mg/kg

Nitrosamines, such as N-nitrosomethylethylamine, can be formed in the atmosphere at night-time by reaction of atmospheric amines with nitrous acid, which is formed by the reaction of nitrous oxides with water vapor(1); N-nitrosomethylethylamine is expected to form from methylethyl amine or from any tertiary amine that contains at least one ethyl and one methyl function(1). N-Nitrosomethylethylamine has been identified as a chemical component in tobacco(2).

No evidence was found that N-nitrosomethylethylamine has been produced commercially(1). N-Nitrosomethylethylamine has been detected in mainstream and sidestream tobacco smoke from cigarettes and cigars(1-4). N-Nitrosomethylethylamine can be produced during commercial water disinfection processes involving ozone/OCl(5).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 43(SRC), determined from a structure estimation method(2), indicates that N-nitrosomethylethylamine is expected to have very high mobility in soil(SRC). Volatilization of N-nitrosomethylethylamine from moist soil surfaces may be an important fate process(SRC) given an estimated Henry's Law constant of 1.44X10-6 atm-cu m/mole(SRC), using a fragment constant estimation method(2). N-Nitrosomethylethylamine is expected to volatilize from dry soil surfaces(SRC) based upon a an estimated vapor pressure of 1.1 mm Hg at 20 °C(3). Nitrosamines (such as N-nitrosomethylethylamine) photolyze rapidly in aqueous solution(4,5); therefore, photolysis is expected to occur on soil surfaces exposed to sunlight(SRC). N-Nitrosomethylethylamine has been shown to biodegrade slowly in anaerobic tests using digester sludge inocula(6).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 43(SRC), determined from a structure estimation method(2), indicates that N-nitrosomethylethylamine is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected at occur slowly(3) based upon an estimated Henry's Law constant of 1.44X10-6 atm-cu m/mole at 25 °C(SRC), developed using a fragment constant estimation method(2). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 24 and 177 days, respectively(SRC). According to a classification scheme(4), an estimated BCF of 3(SRC), from its log Kow of 0.04(5) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Nitrosamines (such as N-nitrosomethylethylamine) photolyze rapidly in aqueous solution(6); at a solar zenith angle of 40 deg N, the photolysis half-life of N-nitrosomethylethylamine and similar nitrosamines at the water's surface (exposed to full sunlight) is about 5.8 min(6). The direct photolysis rate constant for N-nitrosomethylethylamine in aqueous solution exposed to irradiation representing Southern California midsummer, midday sun was observed to be 0.049/min with a half-life of 15 minutes and a quantum yield was 0.61(7). N-Nitrosomethylethylamine is reported to be relatively resistant to aqueous hydrolysis(8). N-Nitrosomethylethylamine has been shown to biodegrade slowly in anaerobic tests using digester sludge inocula(9).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), N-nitrosomethylethylamine, which has an estimated vapor pressure of 1.1 mm Hg at 20 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase N-nitrosomethylethylamine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1.6 days(SRC), calculated from its rate constant of 1.0X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Vapor-phase N-nitrosomethylethylamine may degrade readily via direct photolysis(SRC) based on rapid degradation in aqueous solution which has estimated half-lives of 5.8 minutes at a solar zenith angle of 40 deg N(4) and 15 minutes under California midsummer, midday sun irradiation(5).

The rate constant for the vapor-phase reaction of N-nitrosomethylethylamine with photochemically-produced hydroxyl radicals has been estimated as 1.0X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 1.6 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). N-Nitrosomethylethylamine absorbs light in the environmental spectrum (>290 nm) and is reported to be photochemically reactive and sensitive to UV light(2). Nitrosamines (such as N-nitrosomethylethylamine) are reported to photolyze rapidly in aqueous solution and in the gas-phase with a rate constant of about 0.12/min in sunlight at a zenith angle of 40 deg N(3); this corresponds to half-life of about 5.8 min(SRC). The direct photolysis rate constant for N-nitrosomethylethylamine in aqueous solution exposed to irradiation representing Southern California midsummer, midday sun was observed to be 0.049/min with a half-life of 15 minutes; the quantum yield was 0.61(4). N-Nitrosomethylethylamine is reported to be relatively resistant to aqueous hydrolysis(2).

An estimated BCF of 3 was calculated in fish for N-nitrosomethylethylamine(SRC), using a log Kow of 0.04(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests that bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of N-nitrosomethylethylamine can be estimated to be 43(SRC). According to a classification scheme(2), this estimated Koc value suggests that N-nitrosomethylethylamine is expected to have very high mobility in soil.

The Henry's Law constant for N-nitrosomethylethylamine is estimated as 1.44X10-6 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This value indicates that N-nitrosomethylethylamine is expected to volatilize slowly from water surfaces(2). Based on this Henry's Law constant, the estimated volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 24 days(2,SRC). The estimated volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 177 days(2,SRC). N-Nitrosomethylethylamine's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). N-Nitrosomethylethylamine is expected to volatilize from dry soil surfaces(SRC) based upon a an estimated vapor pressure of 1.1 mm Hg at 20 °C(3).

DRINKING WATER: N-Nitrosomethylethylamine was detected in source and finished drinking water samples collected in China at total nitrosamine concentrations of no detection-42.4 ng/L (detection limits of 0.1-0.9 ng/L)(1).|SURFACE WATER: N-Nitrosomethylethylamine was detected in six of seven surface water samples collected from river and lake sites in Canada and the US in 2006 at concentrations ranging from 0 to 0.55 ng/L(1); concentrations increased after commercial disinfection treatment via ozone/OCl(1).

N-Nitrosomethylethylamine was found at levels of 1.1 ug/kg in 1 of 6 samples of smoked horsemeat and at levels of 0.2 ug/kg in 1 of 5 luncheon meats(1). Concentrations of 0.2 ug/kg have been reported in bacon and chicken and in complete meals containing mushrooms(1); concentrations of 1 ug/kg have been reported for cured meats(1).

N-Nitrosomethylethylamine was qualitatively detected in the workplace air of a rocket fueling facility(1).|The general population will be exposed to N-nitrosomethylethylamine via inhalation of tobacco smoke and ingestion of food containing N-nitrosomethylethylamine(SRC). N-Nitrosomethylethylamine has been detected in mainstream and sidestream tobacco smoke from cigarettes and cigars(1-3). N-Nitrosomethylethylamine has also been detected in various food products such as smoked and cured meats(1); in general, nitrosamines have been identified in foods processed with nitrites or nitrates(2).

... Adult male Fischer 344 rats received a single i.p. or p.o. dose (4.4 mg/kg, 0.05 mmol/kg) of N-nitrosomethylethylamine, (14C)-labeled in either the methyl or ethyl group (survival time, 4 hr). DNA was analyzed by Sephasorb-HP chromatography following acid hydrolysis in 0.1 M HCl. Concentrations of 7-methylguanine in hepatic DNA were 170-200 times higher than those of 7-ethylguanine. This is approximately 2.6 times the 7-methylguanine: 7-ethylguanine ratio of 68, observed when DNA is reacted in vitro with equimolar amounts of the direct alkylating agents N-nitrosomethylurea and N-nitrosoethylurea, suggesting that hydroxylation at the alpha-position of the ethyl group of N-nitrosomethylethylamine proceeds at about 2.6 times the rate as at the methyl group. Concentrations of 7-methylguanine in liver were approximately 15 times higher than in kidney, 100 times higher than in esophagus, and 200 times higher than in lung. Addition of ethanol to the drinking water (5%) caused a slight interorgan shift in metabolism with a decrease in the 7-methylguanine ratio for liver: esophagus by 50% and an increase in the 7-methylguanine ratio for liver: kidney by 40%.|OThe oxidative dealkylation of ... methylethylnitrosamine (MEN) by Sprague-Dawley rat liver microsomes was studied by a colorimetric assay for the simultaneous analysis of formaldehyde and acetaldehyde. Dealkylation in each instance followed Michaelis-Menten kinetics. ... Km values for demethylation and deethylation of MEN were intermediate between those for dimethylnitrosamine and diethylnitrosamine. ...|Possible relationships between structure and metabolism of nitrosamines have been investigated in the rat small intestine. Isolated segments of jejunum and ileum were perfused from the luminal side for 2 hr with a Tyrode solution containing one of four symmetrical dialkylnitrosamines with 2-5 carbon atoms per side chain, all (14)C-labeled at the alpha position, or one of two unsymmetrical nitrosamines, N-nitroso-tert-butylmethylamine and N-nitrosomethylbenzylamine, (14)C-labeled in the methyl group. Besides measurement of (14)C to intestinal tissue, the absorbed fluid (absorbate) as well as the perfusion medium and tissue homogenates were analysed by for the presence of polar metabolites to assess the intestinal metabolism of nitrosamines. Neither N-nitrosodiethylamine nor the two unsymmetrical nitrosamines were metabolized to any significant extent.|Ethylmethylnitrosamine has known human metabolites that include N-Nitrosoethanamine and N-Nitrosomethylamine.

Carcinogens

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Organic bases/Amines and related compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with dry sterile dressings after decontamination ... . /Organic bases/Amines and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. If patient is unresponsive to these measures, vasopressors may be helpful. Watch for signs of fluid overload ... . Administer 1% solution methylene blue if patient is symptomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Organic bases/Amines and related compounds/|Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Nitrates, nitrites, and related compounds/|For more Antidote and Emergency Treatment (Complete) data for N-NITROSOMETHYLETHYLAMINE (6 total), please visit the HSDB record page.

/GENOTOXICITY/ The role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines was examined by Ames test using genetically engineered Salmonella typhimurium (S. typhimurium)YG7108 cells expressing each form of human CYP together with human NADPH-cytochrome P450 reductase (OR). The relationship between the structure of N-alkylnitrosamines and CYP form(s) involved in the activation was evaluated. Eleven strains of S. typhimurium YG7108 cells expressing each form of CYP (CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4 or CYP3A5) were employed. Eight N-alkylnitrosamines including ... N-nitrosomethylethylamine (NMEA) ... were examined. ... N-alkylnitrosamines with relatively short alkyl chains such as ... NMEA were primarily activated by CYP2E1 as judged by mutagen-producing capacity. ...

ethylmethylnitrosamine

ESSENTIALLY 100% AS A RESEARCH CHEMICAL

Method: OSHA 38; Procedure: gas chromatography and detection with a thermal energy analyzer; Analyte: N-nitrosomethylethylamine; Matrix: air; Detection Limit: 0.13 ug/cu m (0.036 ppb).|Volatile N-nitrosamines were confirmed in foods at concentrations of less than 10 micrograms/kg by full scan low resolution mass spectrometry. Ground samples were vacuum-distilled from mineral oil and condensed in liquid nitrogen-cooled vapor traps. The thawed distillate was extracted, the extract was cleaned up and concentrated, and the N-nitrosamine content was determined by combined gas chromatograph-thermal energy analysis. Positive samples were further cleaned up, trapped from a gas chromatographic column, and purged into a gas chromatograph-mass spectrometer for qualitative confirmation by full scan low resolution mass spectrometry. This procedure was applied to foods spiked at 1 microgram/kg and to fried commercial bacons with volatile N-nitrosamine contents of 2 to 5 micrograms/kg. /N-Nitrosamines/|Method: EPA-EAD 1625; Procedure: gas chromatography/mass spectrometry; Analyte: N-nitrosomethylethylamine; Matrix: water; Detection Limit: not provided.|Method: EPA-RCA 8270D; Procedure: gas chromatography/mass spectrometry; Analyte: N-nitrosomethylethylamine; Matrix: solid waste matrices, soils, air sampling media and water; Detection Limit: not provided.|For more Analytic Laboratory Methods (Complete) data for N-NITROSOMETHYLETHYLAMINE (7 total), please visit the HSDB record page.

A gas chromatographic method coupled with a thermal energy analyzer was developed for the quantitative analysis of nitrosamines in the urine of workers & bottle-fed babies. /Nitrosamines/

Health Hazards -> Carcinogens