3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, chloride (1:2)
-
![3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, chloride (1:2) structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/5439c46b484d4b84b6e669153f064280.png "3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, chloride (1:2)")
3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, chloride (1:2)
structure -
-
CAS No:
23476-83-7
-
Formula:
C18H36Cl2N4O2.2Cl
-
Chemical Name:
3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, chloride (1:2)
-
Synonyms:
3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane,3,12-bis(3-chloro-2-hydroxypropyl)-,chloride (1:2);3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane,3,12-bis(3-chloro-2-hydroxypropyl)-,dichloride;Prospidin;Prospidine;NSC 166100;Prospidium chloride;3,12-Bis(3-chloro-2-hydroxypropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane dichloride
-
CAS No:
Description
Prospidium Chloride is an dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophage. Prospidin has good anti-lupus activity due to its immunosuppressive effects and was also used in refractory rheumatoid arthritis as an anti-rheumatic drug. (NCI04)|An antineoplastic dispiropiperazine derivative.
3,12-Diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, chloride (1:2) Basic Attributes
482.3 g/mol
482.156287 g/mol
7G733H6RES
C29333
Drug Information
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)|Drugs that are used to treat RHEUMATOID ARTHRITIS. (See all compounds classified as Antirheumatic Agents.)
Chloride, Prospidium
Computed Properties
Molecular Weight:482.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:482.156287
Monoisotopic Mass:480.159237
Topological Polar Surface Area:46.9
Heavy Atom Count:28
Complexity:389
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Request for Quotation