Ornithine, 2-(difluoromethyl)-, hydrochloride (1:?)
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Ornithine, 2-(difluoromethyl)-, hydrochloride (1:?)
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CAS No:
81645-68-3
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Formula:
C6H12F2N2O2.xClH
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Chemical Name:
Ornithine, 2-(difluoromethyl)-, hydrochloride (1:?)
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Synonyms:
Ornithine,2-(difluoromethyl)-,hydrochloride (1:?);Ornithine,2-(difluoromethyl)-,hydrochloride
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CAS No:
Description
An inhibitor of ornithine decarboxylase, the rate limiting enzyme of the polyamine biosynthetic pathway.
Ornithine, 2-(difluoromethyl)-, hydrochloride (1:?) Basic Attributes
218.63 g/mol
218.0633617 g/mol
269-532-0
270295
DTXSID4045765
D11AX
Drug Information
Treatment of facial hirsutism in women.
Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA. (See all compounds classified as Trypanocidal Agents.)|Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)|Substances and drugs that inhibit or block the activity of ORNITHINE DECARBOXYLASE. (See all compounds classified as Ornithine Decarboxylase Inhibitors.)
alpha Difluoromethyl Ornithine
Ornithine, 2-(difluoromethyl)-, hydrochloride (1:?) Use and Manufacturing
Human drugs -> Vaniqa -> EMA Drug Category|Other dermatological preparations -> Human pharmacotherapeutic group|Human drugs -> Rare disease (orphan)|Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:218.63
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:218.0633617
Monoisotopic Mass:218.0633617
Topological Polar Surface Area:89.3
Heavy Atom Count:13
Complexity:166
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Learn More Other Chemicals
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Ornithine, hydrochloride (1:1)
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Ornithine, hydrochloride (1:?)
22834-83-9
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Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1)
96020-91-6
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