Remifentanil hydrochloride
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Remifentanil hydrochloride
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CAS No:
132539-07-2
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Formula:
C20H28N2O5.ClH
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Chemical Name:
Remifentanil hydrochloride
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Synonyms:
1-Piperidinepropanoic acid,4-(methoxycarbonyl)-4-[(1-oxopropyl)phenylamino]-,methyl ester,hydrochloride (1:1);1-Piperidinepropanoic acid,4-(methoxycarbonyl)-4-[(1-oxopropyl)phenylamino]-,methyl ester,monohydrochloride;GI 87084B;Remifentanil hydrochloride;GG 084;Remifentanyl hydrochloride
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CAS No:
Description
Ultiva is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|Remifentanil Hydrochloride is the hydrochloride salt form of remifentanil, a synthetic anilidopiperidine derivative and short-acting opiate agonist with analgesic and anesthetic properties. Remifentanil selectively binds to and activates the mu-opioid receptor, thereby producing analgesia, respiratory depression, miosis, reduced gastrointestinal motility, and euphoria.|A piperidine-propionate derivative and opioid analgesic structurally related to FENTANYL. It functions as a short-acting MU OPIOID RECEPTOR agonist, and is used as an analgesic during induction or maintenance of general anesthesia, following surgery, during childbirth, and in mechanically ventilated patients under intensive care.
Remifentanil hydrochloride Basic Attributes
412.9 g/mol
412.1764997 g/mol
5V444H5WIC
9739
DTXSID50157614
C47702
Safety Information
|Danger|H300 (11.27%): Fatal if swallowed [Danger Acute toxicity, oral]|P201, P202, P260, P261, P262, P264, P270, P271, P272, P280, P281, P284, P301+P310, P302+P350, P302+P352, P304+P340, P307+P311, P308+P313, P310, P312, P314, P320, P321, P322, P330, P333+P313, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 72 companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)
3-(4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic acid methyl ester
Remifentanil|Ultiva|9739|Schedule II - Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|Yes
Remifentanil hydrochloride Use and Manufacturing
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:412.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:412.1764997
Monoisotopic Mass:412.1764997
Topological Polar Surface Area:76.2
Heavy Atom Count:28
Complexity:523
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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