Fenoprofen calcium
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Fenoprofen calcium
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CAS No:
34597-40-5
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Formula:
C15H14O3.1/2Ca
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Chemical Name:
Fenoprofen calcium
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Synonyms:
Benzeneacetic acid,α-methyl-3-phenoxy-,calcium salt (2:1);Benzeneacetic acid,α-methyl-3-phenoxy-,calcium salt,(±)-;Benzeneacetic acid,α-methyl-3-phenoxy-,calcium salt;Calcium fenoprofen;Fenoprofen calcium;Nalfon;2-(3-Phenoxyphenyl)propionic acid calcium salt;Trandor;56367-29-4;63815-35-0;1260485-60-6
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CAS No:
Description
Fenoprofen calcium (anhydrous) is the anhydrous form of the calcium salt of fenprofen. The dihydrate form is used as a non-steroidal anti-inflammatory drug for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It has a role as a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. It contains a fenoprofen(1-).|A propionic acid derivative that is used as a non-steroidal anti-inflammatory agent.
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.|Aggregated GHS information provided by 2 companies from 1 notifications to the ECHA C&L Inventory.
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)|Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)
Fenoprofen
Fenoprofen calcium Use and Manufacturing
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:522.6
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:522.1355294
Monoisotopic Mass:522.1355294
Topological Polar Surface Area:98.7
Heavy Atom Count:37
Complexity:265
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
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