4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, calcium salt (1:1)

Nedocromil calcium is an organic calcium salt. It contains a nedocromil(2-).|Nedocromil Calcium is the calcium salt form of nedocromil, a pyranoquinolone derivative with anti-inflammatory properties. Nedocromil inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets. As a result, nedocromil sodium inhibits both immediate and late bronchoconstriction, decreases bronchial hyperresponsiveness and inhibits recruitment of other inflammatory cells into the airway epithelium.|A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including EOSINOPHILS; NEUTROPHILS; MACROPHAGES; MAST CELLS; MONOCYTES; AND PLATELETS.

Molecular Weight:409.4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:409.0474427
Monoisotopic Mass:409.0474427
Topological Polar Surface Area:127
Heavy Atom Count:28
Complexity:742
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes