N,N'-Trimethylenebis(actobionamide) hexadecakis sulphate (ester)
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N,N'-Trimethylenebis(actobionamide) hexadecakis sulphate (ester)
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CAS No:
123123-68-2
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Formula:
C27H50N2O70S16
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Chemical Name:
N,N'-Trimethylenebis(actobionamide) hexadecakis sulphate (ester)
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Synonyms:
aprosulate;LW 10082;LW-10082;Aprosulate;UNII-X94B38CQOM;X94B38CQOM;123123-68-2;SCHEMBL9323945;CHEMBL2110864;DTXSID80153866;N,N'-Trimethylenebis(actobionamide) hexadecakis sulfate (ester);N,N'-Trimethylenebis(actobionamide) hexadecakis sulphate (ester);Q27293705;[(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5R)-6-oxo-1,2,4,5-tetrasulfooxy-6-[3-[[(2R,3S,4R,5R)-2,3,5,6-tetrasulfooxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trisulfooxy-6-(sulfooxymethyl)oxan-2-yl]oxyhexanoyl]amino]propylamino]hexan-3-yl]oxy-3,5-disulfooxy-6-(sulfooxymethyl)oxan-
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CAS No:
Description
Aprosulate is a synthetic sulfated bis(lactobionic acid amide) derivative and heparin analogue with anticoagulant activity. Aprosulate is made up of two fully sulfated lactobionic acid moieties with a diamine spacer via two amide bonds. This agent inhibits thrombin by antagonizing heparin cofactor II (HCII) and thus prevents thrombin-induced platelet aggregation. It prolongs clotting time.
N,N'-Trimethylenebis(actobionamide) hexadecakis sulphate (ester) Basic Attributes
2035.7 g/mol
2033.5945617 g/mol
X94B38CQOM
DTXSID80153866
C87428
Drug Information
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. (See all compounds classified as Fibrinolytic Agents.)|Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)
aprosulate
Computed Properties
Molecular Weight:2035.7
XLogP3:-17.5
Hydrogen Bond Donor Count:18
Hydrogen Bond Acceptor Count:70
Rotatable Bond Count:52
Exact Mass:2033.5945617
Monoisotopic Mass:2033.5945617
Topological Polar Surface Area:1250
Heavy Atom Count:115
Complexity:4940
Defined Atom Stereocenter Count:18
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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