Tocainide hydrochloride
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Tocainide hydrochloride
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CAS No:
71395-14-7
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Formula:
C11H16N2O.ClH
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Chemical Name:
Tocainide hydrochloride
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Synonyms:
Propanamide,2-amino-N-(2,6-dimethylphenyl)-,hydrochloride (1:1);Propanamide,2-amino-N-(2,6-dimethylphenyl)-,monohydrochloride,(±)-;Propanamide,2-amino-N-(2,6-dimethylphenyl)-,monohydrochloride;2-Amino-2′,6′-propionoxylidide hydrochloride;Tocainide hydrochloride;Tonocard;Taquidil;Xylotocan;35891-93-1
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CAS No:
Description
An antiarrhythmic agent which exerts a potential- and frequency-dependent block of SODIUM CHANNELS.
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 40 companies from 1 notifications to the ECHA C&L Inventory.
Drug Information
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)|A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS. (See all compounds classified as Voltage-Gated Sodium Channel Blockers.)
Hydrochloride, Tocainide
Tocainide hydrochloride Use and Manufacturing
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:228.72
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:228.1029409
Monoisotopic Mass:228.1029409
Topological Polar Surface Area:55.1
Heavy Atom Count:15
Complexity:196
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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