 Home > Encyclopedia > (+)-Duocarmycin SA

(+)-Duocarmycin SA

(+)-Duocarmycin SA structure

CAS No:
130288-24-3
Formula:
C25H23N3O7
Chemical Name:
(+)-Duocarmycin SA
Synonyms:
Cyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylic acid,1,2,4,5,8,8a-hexahydro-4-oxo-2-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-,methyl ester,(7bR,8aS)-;Cyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylic acid,1,2,4,5,8,8a-hexahydro-4-oxo-2-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-,methyl ester,(7bR)-;Duocarmycin SA;Antibiotic DC 113;(+)-Duocarmycin SA
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Request for Quotation

(+)-Duocarmycin SA Basic Attributes

Molecular Weight：

477.5 g/mol

Exact Mass：

477.47

Characteristics

PSA：

123 Å²

Drug Information

MeSH：

A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026) (See all compounds classified as Antineoplastic Agents, Alkylating.)|Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. (See all compounds classified as Antibiotics, Antineoplastic.)

MeSH Entry Terms：

(+)-duocarmycin SA

Computed Properties

Molecular Weight:477.5
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:477.15360008
Monoisotopic Mass:477.15360008
Topological Polar Surface Area:123
Heavy Atom Count:35
Complexity:971
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of (+)-Duocarmycin SA

Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

high quality Duocarmycin SA 99% transparent liquid KANBEI

CAS No.: 130288-24-3

Grade: Industrial Grade

Content: 99%

Inquiry