15H-Pyrrolo(2,1-f)(1,15,4,7,10,20)dioxatetraazacyclotricosine, cyclic peptide deriv.
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15H-Pyrrolo(2,1-f)(1,15,4,7,10,20)dioxatetraazacyclotricosine, cyclic peptide deriv.
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CAS No:
77327-04-9
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Formula:
C49H78N6O12
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Chemical Name:
15H-Pyrrolo(2,1-f)(1,15,4,7,10,20)dioxatetraazacyclotricosine, cyclic peptide deriv.
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Synonyms:
didemnin A;didemnin A, N-(1-(2-hydroxy-1-oxopropyl)-L-prolyl)-, (S)-;didemnin A, N-(2-hydroxy-1-oxopropyl)-, (S)-;didemnin B;didemnin C;didemnin D;didemnin E;didemnins;NSC 325319;oncoprecipitin A;Didemnin A;didemnins;UNII-4LSZ9C5HOB;4LSZ9C5HOB;Oncoprecipitin A;77327-04-9;NSC 351910;didemnin-a;(3S-(1(2R*,4R*),3R*,4S*,5R*))-N-(1-(N-(4-((3-Hydroxy-5-methyl-4-((N-(N-methyl-D-leucyl)-L-threonyl)amino)-1-oxoheptyl)oxy)-2,5-dimethyl-1,3-dioxohexyl)-L-leucyl)-L-prolyl)-N,O-dimethyl-L-tyrosine phi-lactone;CHEMBL499943;SCHEMBL13413231;L-Tyrosine, N-(1-(N-(4-((3-hydroxy-5-methyl-4-((N-(N-methyl-D-leucyl)-L-threonyl)amino)-1-oxoheptyl)oxy)-2,5-dimethyl-1,3-dioxohexyl)-L-leucyl)-L-prolyl)-N,O-dimethyl-, phi-lactone, (3S-((2R*,4R*),3R*,4S*,5R*))-;Q27260029;15H-Pyrrolo(2,1-f)(1,15,4,7,10,20)dioxatetraazacyclotricosine, cyclic peptide deriv.;(2R)-N-[(3S,6S,8S,12S,13R,16S,17R,20S,23S)-12-hydroxy-3-isobutyl-8-isopropyl-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-13-[(1S)-1-methylpropyl]-2,5,7,10,15,19,22-heptaoxo-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]-4-methyl-2-(methylamino)pentanamide;(2R)-N-[(3S,6S,8S,12S,13R,16S,17R,20S,23S)-13-[(2S)-butan-2-yl]-12-hydroxy-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-2,5,7,10,15,19,22-heptaoxo-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]-4-methyl-2-(m;(R)-N-((3S,6R,7S,10R,11S,15S,17S,20S,25aS)-10-((S)-sec-butyl)-11-hydroxy-20-isobutyl-15-isopropyl-3-(4-methoxybenzyl)-2,6,17-trimethyl-1,4,8,13,16,18,21-heptaoxodocosahydro-15H-pyrrolo[2,1-f][1,15]dioxa[4,7,10,20]tetraazacyclotricosin-7-yl)-4-methyl-2-(methylamino)pentanamide
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CAS No:
15H-Pyrrolo(2,1-f)(1,15,4,7,10,20)dioxatetraazacyclotricosine, cyclic peptide deriv. Basic Attributes
943.2 g/mol
942.56777194 g/mol
4LSZ9C5HOB
Drug Information
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)|Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)|Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)|Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)
didemnin A
Computed Properties
Molecular Weight:943.2
XLogP3:5.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:13
Exact Mass:942.56777194
Monoisotopic Mass:942.56777194
Topological Polar Surface Area:239
Heavy Atom Count:67
Complexity:1700
Defined Atom Stereocenter Count:11
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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