5-cyclopropyl-7-(2,6-dimethylpyridin-4-yl)-8-fluoro-2-hydroxypyrimido[1,6-a]benzimidazole-1,3-dione
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![5-cyclopropyl-7-(2,6-dimethylpyridin-4-yl)-8-fluoro-2-hydroxypyrimido[1,6-a]benzimidazole-1,3-dione structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/876449f71c414be7bfa7d803c0c159b8.png "5-cyclopropyl-7-(2,6-dimethylpyridin-4-yl)-8-fluoro-2-hydroxypyrimido[1,6-a]benzimidazole-1,3-dione")
5-cyclopropyl-7-(2,6-dimethylpyridin-4-yl)-8-fluoro-2-hydroxypyrimido[1,6-a]benzimidazole-1,3-dione
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CAS No:
155144-64-2
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Formula:
C20H17FN4O3
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Chemical Name:
5-cyclopropyl-7-(2,6-dimethylpyridin-4-yl)-8-fluoro-2-hydroxypyrimido[1,6-a]benzimidazole-1,3-dione
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Synonyms:
Ro 47-3359;Ro-47-3359;Ro 47-3359;155144-64-2;Ro-47-3359;5-Cyclopropyl-7-(2,6-dimethyl-4-pyridinyl)-8-fluoro-2-hydroxypyrimido(1,6-a)benzimidazole-1,3(2H,5H)-dione;CCRIS 8211;5-Cyclopropyl-7-(2,6-dimethyl-4-pyridiyl)-8-fluoro-2-hydroxypyrimido(1,6-a)benzimidazole-1,3(2H,5H)-dione;DTXSID60165821;Pyrimido(1,6-a)benzimidazole-1,3(2H,5H)-dione, 5-cyclopropyl-7-(2,6-dimethyl-4-pyridinyl)-8-fluoro-2-hydroxy-;Pyrimido(1,6-a)benzimidazole-1,3(2H,5H)-dione, 5-cyclopropyl-7-(2,6-dimethyl-4-pyridiyl)-8-fluoro-2-hydroxy-
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CAS No:
5-cyclopropyl-7-(2,6-dimethylpyridin-4-yl)-8-fluoro-2-hydroxypyrimido[1,6-a]benzimidazole-1,3-dione Basic Attributes
380.4 g/mol
380.12846858 g/mol
DTXSID60165821
Drug Information
Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)
Ro 47-3359
Computed Properties
Molecular Weight:380.4
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:380.12846858
Monoisotopic Mass:380.12846858
Topological Polar Surface Area:77
Heavy Atom Count:28
Complexity:716
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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