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Focalin

Focalin structure

Focalin 

structure
  • CAS No:

    19262-68-1

  • Formula:

    C14H19NO2.ClH

  • Chemical Name:

    Focalin

  • Synonyms:

    2-Piperidineacetic acid,α-phenyl-,methyl ester,hydrochloride (1:1),(αR,2R)-;2-Piperidineacetic acid,α-phenyl-,methyl ester,hydrochloride,[R-(R*,R*)]-;2-Piperidineacetic acid,α-phenyl-,methyl ester,hydrochloride,(αR,2R)-(+)-;2-Piperidineacetic acid,α-phenyl-,methyl ester,hydrochloride,(αR,2R)-;d-threo-Methylphenidate hydrochloride;D-threo-Methylphenidate hydrochloride;Dexmethylphenidate hydrochloride;Focalin;35652-13-2

Description

Ritalin is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|Dexmethylphenidate Hydrochloride is a synthetic sympathomimetic amine with CNS stimulating properties. Dexmethylphenidate hydrochloride acts by facilitating the release of catecholamines, particularly noradrenaline and dopamine, from nerve terminals in the brain and inhibits their uptake. This leads to an increase in motor activity, causes euphoria, mental alertness and excitement and suppresses appetite. This drug causes dependence and may cause an increase in heart rate and blood pressure. It is used in the treatment of attention deficit hyperactivity disorder. It may also be used in the treatment of fatigue and other nervous system effects seen with chemotherapy.|A methylphenidate derivative, DOPAMINE UPTAKE INHIBITOR and CENTRAL NERVOUS SYSTEM STIMULANT that is used in the treatment of ATTENTION DEFICIT HYPERACTIVITY DISORDER.

Focalin Basic Attributes

269.77 g/mol

269.1182566 g/mol

1678OK0E08

1724

C47480

Characteristics

38.3 Ų

221-223 °C

Drug Information

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)|Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake. (See all compounds classified as Dopamine Uptake Inhibitors.)

Dexmethylphenidate

Methylphenidate|Concerta, Ritalin, Methylin|1724|Schedule II - Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|No

Focalin Use and Manufacturing

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:269.77
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:269.1182566
Monoisotopic Mass:269.1182566
Topological Polar Surface Area:38.3
Heavy Atom Count:18
Complexity:249
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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