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Home > Encyclopedia > 4-tert-butyl-N-methyl-N-phenylbenzamide

4-tert-butyl-N-methyl-N-phenylbenzamide

4-tert-butyl-N-methyl-N-phenylbenzamide structure

4-tert-butyl-N-methyl-N-phenylbenzamide 

structure
  • CAS No:

    70019-98-6

  • Formula:

    C18H21NO

  • Chemical Name:

    4-tert-butyl-N-methyl-N-phenylbenzamide

  • Synonyms:

    Antigen, CD10;Antigens, CD10;Antigens, Leukemia, Common Acute Lymphoblastic;Atriopeptidase;CALLA Antigen;Carboxypeptidase, Enkephalin Dipeptidyl;CD10 Antigen;CD10 Antigens;Common Acute Lymphoblastic Leukemia Antigens;Dipeptidyl Carboxypeptidase, Enkephalin;Endopeptidase 24.11;Endopeptidase 24.11, Neutral;Endopeptidase, Neutral;Endopeptidase-24.11;Enkephalin Dipeptidyl Carboxypeptidase;Enkephalinase;Enkephalinase 24.11;Enkephalinase-24.11;Enzyme, YGG-Forming;Kidney Brush Border Neutral Proteinase;Kidney-Brush-Border Neutral Proteinase;Membrane Metallo Endopeptidase;Membrane Metallo-Endopeptidase;Metallo-Endopeptidase, Membrane;Metalloendopeptidase, Thermolysin-Like;Neprilysin;Neutral Endopeptidase;Neutral Endopeptidase 24.11;Neutral Proteinase, Kidney-Brush-Border;Thermolysin Like Metalloendopeptidase;Thermolysin-Like Metalloendopeptidase;YGG Forming Enzyme;YGG-Forming Enzyme;4-tert-butyl-N-methyl-N-phenylbenzamide;70019-98-6;Carboxypeptidase, enkephalin dipeptidyl;SCHEMBL21652177;DTXSID50990265;ZINC126207;AKOS004084072;MCULE-7563946631;ST014468;[4-(tert-butyl)phenyl]-N-methyl-N-benzamide;AO-854/40326690

Description

Enzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA Antigen), an important marker in the diagnosis of human acute lymphocytic leukemia. There is no relationship with CALLA PLANT.

4-tert-butyl-N-methyl-N-phenylbenzamide Basic Attributes

267.4 g/mol

267.162314293 g/mol

Characteristics

20.3 Ų

Safety Information

|Warning|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Antigen, CD10

Computed Properties

Molecular Weight:267.4
XLogP3:4
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:267.162314293
Monoisotopic Mass:267.162314293
Topological Polar Surface Area:20.3
Heavy Atom Count:20
Complexity:317
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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