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Home > Encyclopedia > 10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride

10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride

10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride structure

10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride 

structure
  • CAS No:

    5317-37-3

  • Formula:

    C20H27Cl2N3S

  • Chemical Name:

    10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride

  • Synonyms:

    Dihydrochloride, Perazine;Maleate, Perazine;Perazine;Perazine Dihydrochloride;Perazine Maleate;Perazine Maleate (1:1);Perazine Maleate (1:2);Pernazine;Taxilan;Perazine Dihydrochloride;5317-37-3;Taxilan dihydrochloride;10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride;Taxilan HCl;10-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazine dihydrochloride;SCHEMBL2237726;DTXSID70967691;10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazine Dihydrochloride;AKOS030242382;Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-, dihydrochloride;FT-0673626;10-[3-(4-Methylpiperazin-1-yl)propyl]-10H-phenothiazine--hydrogen chloride (1/2)

Description

A phenothiazine antipsychotic with actions and uses similar to those of CHLORPROMAZINE. Extrapyramidal symptoms may be more common than other side effects.

10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride Basic Attributes

412.4 g/mol

411.1302744 g/mol

Characteristics

35 Ų

Drug Information

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)|Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)

Dihydrochloride, Perazine

Computed Properties

Molecular Weight:412.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:411.1302744
Monoisotopic Mass:411.1302744
Topological Polar Surface Area:35
Heavy Atom Count:26
Complexity:374
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Guide of 10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;dihydrochloride

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