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Home > Encyclopedia > 6,11-dihydrothiochromeno[4,3-b]indole

6,11-dihydrothiochromeno[4,3-b]indole

6,11-dihydrothiochromeno[4,3-b]indole structure

6,11-dihydrothiochromeno[4,3-b]indole 

structure
  • CAS No:

    4079-26-9

  • Formula:

    C15H11NS

  • Chemical Name:

    6,11-dihydrothiochromeno[4,3-b]indole

  • Synonyms:

    6,11-dihydro-5-thia-11-aza-benzo(a)-fluorene;PD 146176;PD-146176;PD 146176;4079-26-9;pd146176;PD-146176;6,11-dihydrothiochromeno[4,3-b]indole;6,11-Dihydro[1]benzothiopyrano[4,3-b]indole;NSC168807;CHEMBL180917;6,11-dihydro-[1]benzothiopyrano[4,3-b]indole;6,3-b]indole;NSC 168807;6,11-Dihydro-5-thia-11-aza-benzo(a)fluorene;SCHEMBL1986281;ZINC6892;GTPL11390;AOB5548;DTXSID20961205;CHEBI:173098;BCP24885;EX-A3327;BDBM50208823;MFCD05664738;AKOS024457313;NSC-168807;[1]Benzothiopyrano[4, 6,11-dihydro-;NCGC00165868-01;DS-017019;HY-103157;B7208;CS-0024982;EC-000.2427;PD 146176, >=98% (HPLC), solid;(1)Benzothiopyrano(4,3-b)indole, 6,11-dihydro-

Description

PD-146176 is an organic heterotetracyclic compound that is 1H-indole which is ortho-fused to a 2H-1-benzothiopyran group at positions 2-3. It is an inhibitor of 15-lipoxygenase that limits atherosclerotic lesion development in rabbits. It has a role as a ferroptosis inhibitor, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor and an antiatherogenic agent. It is an organic heterotetracyclic compound, an organosulfur heterocyclic compound and an organonitrogen heterocyclic compound.

6,11-dihydrothiochromeno[4,3-b]indole Basic Attributes

237.32 g/mol

237.06122053 g/mol

168807

Characteristics

41.1 Ų

Drug Information

6,11-dihydro-5-thia-11-aza-benzo(a)-fluorene

Computed Properties

Molecular Weight:237.32
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:237.06122053
Monoisotopic Mass:237.06122053
Topological Polar Surface Area:41.1
Heavy Atom Count:17
Complexity:293
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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