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Oleandolide

Oleandolide structure

Oleandolide 

structure
  • CAS No:

    68540-16-9

  • Formula:

    C20H34O7

  • Chemical Name:

    Oleandolide

  • Synonyms:

    Oleandolide;1,9-Dioxaspiro[2.13]hexadecane,oleandolide deriv.;1,9-Dioxaspiro[2.13]hexadecane-4,10-dione,6,12,14-trihydroxy-5,7,8,11,13,15-hexamethyl-,[3R-(3R*,5R*,6S*,7R*,8R*,11R*,12S*,13R*,14S*,15S*)]-;[3R-(3R*,5R*,6S*,7R*,8R*,11R*,12S*,13R*,14S*,15S*)]-6,12,14-Trihydroxy-5,7,8,11,13,15-hexamethyl-1,9-dioxaspiro[2.13]hexadecane-4,10-dione;Oleandonolide;(-)-Oleandolide

Description

Oleandolide is a 14-membererd macrolide containing ten stereocentres carrying one epoxymethano, three hydroxy and five methyl substituents. It is the aglycone of the antibiotic oleandomycin. It is a macrolide, a cyclic ketone, a triol and a spiro-epoxide.

Oleandolide Basic Attributes

386.5 g/mol

386.48

Characteristics

117 Ų

Drug Information

oleandolide

Oleandolide Use and Manufacturing

Polyketides [PK] -> Macrolides and lactone polyketides [PK04]

Computed Properties

Molecular Weight:386.5
XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Exact Mass:386.23045342
Monoisotopic Mass:386.23045342
Topological Polar Surface Area:117
Heavy Atom Count:27
Complexity:565
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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