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Vitamin E

Vitamin E structure

CAS No:
2074-53-5
Formula:
C29H50O2
Chemical Name:
Vitamin E
Synonyms:
RAC-ALPHA-TOCOPHEROL;2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4R,8R)-4,8,12-trimethyltridecyl-, (2R)-rel-;[2R*(4R*,8R*)]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol;rac-2β*,5,7,8-Tetramethyl-2-[(4R*,8R*)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol;Vitamin E;(+-)-Med-e;(2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol;2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R*(4R*,8R*))-(+-)- (9ci)
Categories:
Cosmetic Ingredient > Antioxidant Ingredient

Description

ChEBI: (R,R,R)-alpha-tocopherol is an alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. It has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite. It is an enantiomer of a (S,S,S)-alpha-tocopherol.

Numerous foods provide vitamin E. Nuts, seeds, and vegetable oils are among the best sources of alpha-tocopherol, and significant amounts are available in green leafy vegetables and fortified cereals. Most vitamin E in American diets is from gamma-tocopherol from soybean, canola, corn, and other vegetable oils and food products. Such as:Wheat germ oil,Sunflower, safflower, and soybean oil. Sunflower seedsAlmondsPeanuts, peanut butterBeet greens, collard greens, spinach. PumpkinRed bell pepper. Asparagus.Mangoes. Avocados.

Vitamin E Basic Attributes

Molecular Weight：

430.71

Exact Mass：

430.71

EC Number：

218-197-9

Color/Form：

Light yellow to yellow

Characteristics

Physical Properties：

Vitamin E has demonstrated some success in the treatment of yellow nail syndrome when taken orally (600 EU to 1200 EU daily) for several months. Topically-applied vitamin E has also shown significant improvement in symptoms of yellow nail syndrome, as well as increased nail growth rates after six months.

Density：

0.93

Boiling Point：

485.9±0.0 °C(Predicted)

PKA：

11.40±0.40(Predicted)

Critical Temperature & Pressure：

Store at -20°C,protect from light

Vitamin E Use and Manufacturing

Vitamin E supplement.

vitamin E (D-alpha-tocopherol; DL-alpha-tocopherol; tocopherol) is considered the most important oil-soluble anti-oxidant and freeradical scavenger. Studies indicate that vitamin e performs these functions when topically applied. It is also a photoprotectant, and it helps protect the cellular membrane from free-radical damage. In addition, vitamin e serves a preservative function given its ability to protect against oxidation. This benefits not only the skin, but also the product in terms of longevity. As a moisturizer, vitamin e is well-absorbed through the skin, demonstrating a strong affinity with small blood vessels and an ability to enhance blood circulation in the skin. It is also thought to improve the skin’s water-binding ability. In addition, vitamin e emulsions have been found to reduce transepidermal water loss, thereby improving the appearance of rough, dry, and damaged skin. This vitamin is also believed to help maintain the connective tissue. There is evidence that vitamin e is effective in preventing irritation owing to sun exposure: studies show that vitamin e topically applied prior to uV irradiation is protective against epidermal cell damage caused by inflammation. This indicates possible anti-inflammatory properties. Lipid peroxidation in tissues may be one cause of skin aging. Vitamin e, however, appears to counteract decreased functioning of the sebaceous glands and to reduce excessive skin pigmentation, which is found to increase almost linearly with age. It is available also as a tocopherol-polypeptide complex that delivers the vitamin in a waterdispersable form. In this way, when incorporated into cosmetic formulations, it does not need other compounds to assist in its solubilization. It is useful in anti-aging creams and lotions, and in uV protective products, tocopherol is a naturally occurring vitamin e found in a variety of cereal germ oils including wheat germ oil. It can also be produced synthetically.

Drug Function and Efficacy

It constitutes a variety of coenzymes, participates in the metabolism, utilization and synthesis of a variety of substances, promotes bone growth, maintains the structural integrity of epithelial tissue, and maintains normal growth and development

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Multivitamin tablets
Ingredients	12 vitamins: Vitamin A (4000 IU) 1.2 mg; Vitamin B1 1.6 mg; Vitamin B2 1.8 mg; Vitamin B6 2.6 mg; Vitamin B12 4.0 mg; Vitamin C 0.1 g; Vitamin D3 (500 IU) 12.5 micrograms; Vitamin E 15 mg; Biotin 0.2 mg; Folic acid 0.8 mg; Nicotinamide 19 mg; Calcium pantothenate 10 mg. 7 minerals and trace elements: Calcium 0.125 g; Magnesium 0.1 g; Phosphorus 0.125 g; Copper 1 mg; Iron 60 mg; Manganese 1 mg; Zinc 7.5 mg;
Indication	1. It should not be used with tetracycline drugs. If necessary, the two drugs should be taken at least two hours apart. 2. It should not be used with other drugs containing vitamin A and vitamin D. 3. This product should not be used with carbamazepine, phenytoin, primidone and barbiturates. 4. If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	60s

Vitamin E soft capsules
Ingredients	The main ingredient of each capsule of this product is vitamin E. The auxiliary material is refined edible vegetable oil.
Indication	1. This product can promote the absorption, utilization and liver storage of vitamin A. 2. Drugs that reduce or affect fat absorption, such as cholestyramine, neomycin and sucralfate, can interfere with the absorption of this product and should not be taken together. 3. Oral contraceptives can accelerate the metabolism of vitamin E and lead to vitamin E deficiency. 4. When estrogen is used with this product, if the dosage is large and the treatment course is long, it can induce thrombophlebitis. 5. Avoid using this product with dicoumarol and its derivatives to prevent the occurrence of hypoprothrombinemia. 6. If used with other drugs at the same time, drug interactions may occur. Please consult a physician or pharmacist for details.
Specifications	50mg
Manufacturer	Zhejiang Medicine Co., Ltd.

Vitazyme Capsules
Ingredients	This crystal system is a compound preparation made from soybean as the main raw material, refined and processed after biological fermentation. Its main ingredients are riboflavin and riboflavin derivatives. Among them, there are 12 kinds of vitamins, with B2 and VE having the highest content, 18 kinds of amino acids, 23 kinds of trace elements, and others include sugars, crude fiber, etc.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	0.2g
Manufacturer	Harbin Pharmaceutical Group Co., Ltd. GENERAL Pharm. FACTORY

See More Related Drugs

Registered Holders

Zhejiang Pharmaceutical Co., Ltd. Vitamin Factory

China
Active
Zhejiang Changhai Pharmaceutical Co., Ltd.

China
Active
DSM Vitamins Trading (SHANGHAI) Co., Ltd.

China
Active

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