3-(METHYLSULFONYL)BENZENESULFONYLCHLORIDE

3-Methanesulfonylbenzene-1-sulfonyl chloride Methylsulfonylbenzene (5 g, 32 mmol) was placed into chlorosulfonic acid (37 g, 320 mmol), heated at 90 °Cfor 18 h, and cooled to room temperature. The mixture was slowly poured into crushed ice. The resulting suspensionwas extracted with ethyl acetate (2 3 200 mL). The organic layers were separated, combined, washed with saturatedaqueous NaCl solution (50 mL), and dried with sodium sulfate. After suction filtration, the resulting filtrate was distilledunder reduced pressure. The residue was the intermediate 3-methylsulfonylphenyl-1-sulfonyl chloride (50 mg, yield6.1percent).

Molecular Weight:254.7
XLogP3:1.6
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:253.9474287
Monoisotopic Mass:253.9474287
Topological Polar Surface Area:85
Heavy Atom Count:14
Complexity:386
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes