D(+)-Ribonic acid gamma-lactone
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D(+)-Ribonic acid gamma-lactone
structure -
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CAS No:
5336-08-3
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Formula:
C5H8O5
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Chemical Name:
D(+)-Ribonic acid gamma-lactone
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Synonyms:
D-RIBOSE-LACTONE;D-(+)-RIBONIC ACID GAMMA-LACTON;D(+)-RIBONIC ACID GAMMA-LACTONE;D-(+)-RIBONIC ACID G-LACTONE;D-(+)-RIBONIC GAMMA-LACTONE;D(+)-RIBONO-1,4-LACTONE;D-RIBONO-1,4-LACTONE;D-(+)-RIBONO-GAMMA-LACTONE
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CAS No:
Description
D-Ribonolactone is sugar lactone and an inhibitor of β-galactosidase of Escherichia coli with a Ki of 26 mM[1].
Solid
D-ribono-1,4-lactone is a five-membered form of ribonolactone having D-configuration. It has a role as a metabolite. It is a ribonolactone and a butan-4-olide. It derives from a D-ribonic acid.
White Crystalline Solid
ChEBI: A five-membered form of ribonolactone having D-configuration.
D(+)-Ribonic acid gamma-lactone Basic Attributes
148.11
148.11
82057
226-256-5
64E63NC231
White to Pale Yellow
29322090
Characteristics
86.99000
-1.4
White to Pale Yellow Powder
1.2336 (rough estimate)
85-87 °C(lit.)
188.68°C (rough estimate)
162.8±12.8 °C
18 ° (C=1, H2O)
soluble
-20°C Freezer
18 º (c=5, H2O)
12.10±0.60(Predicted)
Sealed in dry,Room Temperature
D(+)-Ribonic acid gamma-lactone Use and Manufacturing
It can be obtained by oxidation, substitution conversion, substitution and acidification of glucose to generate riboacid, and then heating to lactonize.
Important chiral synthon
A sugar lactone as inhibitor of β-galactosidase of E. coli.
D-ribono-1,4-lactone is a compound useful in organic synthesis.
Cosmetics -> Humectant
Computed Properties
Molecular Weight:148.11
XLogP3:-1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:148.03717335
Monoisotopic Mass:148.03717335
Topological Polar Surface Area:87
Heavy Atom Count:10
Complexity:145
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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