4,6-Diamino-5-formamidopyrimidine
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4,6-Diamino-5-formamidopyrimidine
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CAS No:
5122-36-1
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Formula:
C5H7N5O
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Chemical Name:
4,6-Diamino-5-formamidopyrimidine
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Synonyms:
Formamide,N-(4,6-diamino-5-pyrimidinyl)-;N-(4,6-Diamino-5-pyrimidinyl)formamide;4,6-Diamino-5-formamidopyrimidine;FAPy-adenine;4,6-Diamino-5-(formylamino)pyrimidine
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CAS No:
Description
FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases[1][2][3].
Solid
4,6-diamino-5-formamidopyrimidine is a member of the class of aminopyrimidines that is 4,6-diaminopyrimidine bearing an additional formamido substituent at position 5. A DNA lesion formed when DNA exposed to ionising radiation. It is an aminopyrimidine and a formamidopyrimidine.
Characteristics
106.92000
1.92
Solid
1.4±0.1 g/cm3
224-226 °C
464.7±47.0 °C at 760 mmHg
234.8±29.3 °C
1.674
Computed Properties
Molecular Weight:153.14
XLogP3:-1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:153.06505986
Monoisotopic Mass:153.06505986
Topological Polar Surface Area:107
Heavy Atom Count:11
Complexity:131
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
4,6-Diamino-5-formamidopyrimidine
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