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(-)-Sophocarpine

(-)-Sophocarpine structure

(-)-Sophocarpine 

structure
  • CAS No:

    6483-15-4

  • Formula:

    C15H22N2O

  • Chemical Name:

    (-)-Sophocarpine

  • Synonyms:

    1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one,2,3,6,7,7a,8,13,13a,13b,13c-decahydro-,(7aS,13aR,13bR,13cS)-;Sophocarpine;Matridin-15-one,13,14-didehydro-;(7aS,13aR,13bR,13cS)-2,3,6,7,7a,8,13,13a,13b,13c-Decahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one;(-)-Sophocarpine;13,14-Dehydromatrine;13,14-Didehydromatrine;1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one,2,3,6,7,7a,8,13,13a,13b,13c-decahydro-,[7aS-(7aα,13aβ,13bα,13cα)]-;1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one 2,3,6,7,7a,8,13,13a,13b,13c-decahydro-,(7aS,13aR,13bR,13cS)-;21914-57-8;478614-26-5

  • Categories:

    Cosmetic Ingredient  >  Skin Conditioning

Description

Sophocarpine is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine has been demonstrated to have anti-tumor act

(-)-Sophocarpine Basic Attributes

246.34800

246.35

DTXSID90215126

Characteristics

23.55000

1.52350

1.2±0.1 g/cm3

54-55 °C

170-210 °C @ Press: 5 Torr

194.0±21.1 °C

1.603

Drug Information

13,14-didehydro-matridin-15-one

Computed Properties

Molecular Weight:246.35
XLogP3:1.7
Hydrogen Bond Acceptor Count:2
Exact Mass:246.173213330
Monoisotopic Mass:246.173213330
Topological Polar Surface Area:23.6
Heavy Atom Count:18
Complexity:392
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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