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Chlorphenoxamine

Chlorphenoxamine structure

CAS No:
77-38-3
Formula:
C18H22ClNO
Chemical Name:
Chlorphenoxamine
Synonyms:
Ethanamine,2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethyl-;Ethylamine,2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]-N,N-dimethyl-;2-[1-(4-Chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine;p-Chloro-α-methyldiphenhydramine;2-(p-Chloro-α-methyl-α-phenylbenzyloxy)-N,N-dimethylethylamine;[1-(p-Chlorophenyl)-1-phenylethyl] (β-dimethylaminoethyl) ether;β-Dimethylaminoethyl (p-chloro-α-methylbenzhydryl) ether;Chlorphenoxamine;121944-29-4
Categories:
Organic Chemistry > Amides

Description

Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. Target: Histamine Receptor

Chlorphenoxamine is a diarylmethane. It has a role as an anticoronaviral agent.|Chlorphenoxamine is marketed under the name Phenoxene. It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.

Chlorphenoxamine Basic Attributes

Molecular Weight：

303.83

Exact Mass：

303.83

ATC Code：

D04AA34|D - Dermatologicals|R - Respiratory system

HScode：

2922199090

Characteristics

PSA：

12.5

XLogP3：

4.1

Density：

1.093g/cm3

Melting Point：

128

Boiling Point：

152.5 °C

Flash Point：

185.9ºC

Refractive Index：

1.551

Safety Information

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 38 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)|Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)

MeSH Entry Terms：

chlorphenoxamine

Chlorphenoxamine Use and Manufacturing

Use Classification：

Pharmaceuticals

Computed Properties

Molecular Weight:303.8
XLogP3:4.1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:303.1389920
Monoisotopic Mass:303.1389920
Topological Polar Surface Area:12.5
Heavy Atom Count:21
Complexity:296
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Chlorphenoxamine

Compound Net Biotechnology Inc. Contact Supplier

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Manufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acid

77-38-3 2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine

CAS No.: 77-38-3

Grade: Industrial Grade

Content: 95%

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