Triparanol
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Triparanol
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CAS No:
78-41-1
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Formula:
C27H32ClNO2
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Chemical Name:
Triparanol
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Synonyms:
Benzeneethanol,4-chloro-α-[4-[2-(diethylamino)ethoxy]phenyl]-α-(4-methylphenyl)-;Ethanol,2-(p-chlorophenyl)-1-[p-[2-(diethylamino)ethoxy]phenyl]-1-p-tolyl-;4-Chloro-α-[4-[2-(diethylamino)ethoxy]phenyl]-α-(4-methylphenyl)benzeneethanol;MER 29;2-(p-Chlorophenyl)-1-[p-(β-diethylaminoethoxy)phenyl]-1-(p-tolyl)ethanol;2-p-Chlorophenyl-1-[p-(2-diethylaminoethoxy)phenyl]-1-p-tolylethanol;1-[p-(β-Diethylaminoethoxy)phenyl]-1-(p-tolyl)-2-(p-chlorophenyl)ethanol;1-[4-[2-(Diethylamino)ethoxy]phenyl]-1-(p-tolyl)-2-(p-chlorophenyl)ethanol;Triparanol;TR;Triparin;Tropalin;Diticyl;Trianel;Sclane;Drenaren;Acosterina;Valip;Metasclene;Hipocolestina;Trikosterol;Verdiana;Clotrox;MER 2p;Metasqualene;NSC 65345;144-08-1
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CAS No:
Description
Triparanol is a stilbenoid. It has a role as an anticoronaviral agent.|Antilipemic agent with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.
Characteristics
32.70000
5.84760
1.133g/cm3
103 °C
235-240 °C @ Press: 0.08 Torr
284.5ºC
1.582
2-8ºC
Safety Information
NONH for all modes of transport
3
22-41
26-39
KK2400000
Xn
P280-P305 + P351 + P338
H302-H318
|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)
MER 29
Computed Properties
Molecular Weight:438.0
XLogP3:6.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:10
Exact Mass:437.2121570
Monoisotopic Mass:437.2121570
Topological Polar Surface Area:32.7
Heavy Atom Count:31
Complexity:490
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes