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Methacrylamide

Methacrylamide structure

Methacrylamide 

structure
  • CAS No:

    79-39-0

  • Formula:

    C4H7NO

  • Chemical Name:

    Methacrylamide

  • Synonyms:

    2-Propenamide,2-methyl-;Methacrylamide;2-Methyl-2-propenamide;Methacrylic acid amide;Methacrylic amide;2-Methylpropenamide;2-Methylacrylamide;NSC 23772;NSC 24147

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

white to very slightly yellow crystals


DryPowder


Methacrylamide is a member of acrylamides and a primary carboxamide.

Methacrylamide Basic Attributes

85.1

85.10

605397

201-202-3

K67NG89J77

24147|23772

DTXSID8029600

2924199090

Characteristics

43.1

0.1

White to very slightly yellow Crystals

0.9±0.1 g/cm3

105 °C

215 °C

215°C

1.438

H2O: 202 g/L (20 ºC)

Store below +30°C.

0.0015 hPa (20 °C)

LD50 orally in Rabbit: 1815 mg/kg LD50 dermal Rat > 5000 mg/kg

2-15%(V)

Safety Information

III

6.1(b)

3263

1

22-36/37/38

26-36/37

UC6475000

Xn

P261-P305 + P351 + P338

H302-H315-H319-H335

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P280, P301+P312, P304+P340, P305+P351+P338, P309+P311, P312, P314, P330, P337+P313, P403+P233, P405, and P501|Aggregated GHS information provided by 791 companies from 20 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P264, P270, P281, P301+P312, P305+P351+P338, P308+P313, P309+P311, P314, P330, P337+P313, P405, and P501

Drug Information

methacrylamide

Methacrylamide Use and Manufacturing

Methods of Manufacturing

Sodium cyanide is used as raw material to react with sulfuric acid to obtain hydrocyanic acid. Hydrocyanic acid reacts with acetone to generate acetone cyanohydrin, and then reacts with concentrated sulfuric acid to generate methacrylamide sulfate, which is then neutralized with ammonia to obtain product formaldehyde. Base acrylamide. Sodium cyanide reacts with sulfuric acid to obtain hydrocyanic acid. The methacrylamide sulfate is prepared from hydrocyanic acid, and the production method is the same as that of methacrylic acid. The obtained methacrylamide sulfate is neutralized with ammonia, extracted, crystallized, filtered, and dried at low temperature to obtain a finished product. To produce methacrylamide with sodium cyanide as raw material, 821kg sodium cyanide, 883kg acetone (≥98.5%), 3440kg sulfuric acid and 650kg liquid ammonia are consumed per ton of product.

Uses

Organic Synthesis. Synthesis of polymer compounds.


Coating agent

All other chemical product and preparation manufacturing|2-Propenamide, 2-methyl-: ACTIVE

Computed Properties

Molecular Weight:85.10
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:85.052763847
Monoisotopic Mass:85.052763847
Topological Polar Surface Area:43.1
Heavy Atom Count:6
Complexity:85.5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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