8-Methoxy-2-quinazolinamine
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8-Methoxy-2-quinazolinamine
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CAS No:
708-15-6
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Formula:
C9H9N3O
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Chemical Name:
8-Methoxy-2-quinazolinamine
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Synonyms:
2-Quinazolinamine,8-methoxy-;Quinazoline,2-amino-8-methoxy-;8-Methoxy-2-quinazolinamine;2-Amino-8-methoxyquinazoline
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CAS No:
8-Methoxy-2-quinazolinamine Use and Manufacturing
The 2-chloride 113 was converted into the amine 122 according to standard Chichibabin reaction conditions. The 2-amine 122 (1 mmol) and isocyanate [(1] mmol) in dry CHC13 (10 mL) were then heated under reflux for 16 h. This gave, after filtration, the urea derivative 123. Treatment of 123 with BBr3 gave A124.The 2-chloride 113 was converted into the amine 122 according to standard Chichibabin reaction conditions. The 2-amine 122 (1 mmol) and isocyanate [(1] mmol) in dry CHC13 (10 mL) were then heated under reflux for 16 h. This gave, after filtration, the urea derivative 123. Treatment of 123 with BBr3 gave A124.
Computed Properties
Molecular Weight:175.19
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:175.074561919
Monoisotopic Mass:175.074561919
Topological Polar Surface Area:61
Heavy Atom Count:13
Complexity:176
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes