Arginine

Arginine (abbreviated as Arg or R) is an α-amino acid. It was first isolated in 1886 . The L - form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them. There are some conditions that put an increased demand on the body for the synthesis of L-arginine, including surgical or other trauma, sepsis and burns . Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze.In general, most people do not need to take arginine supplements because the body usually produces enough.

Prisms from water containing two molecules of H2O, anhydrous plates from alcohol solution. Dehydrates at 105C, decomposes at 244C. Sparingly soluble in alcohol; insoluble in ether.

An essential amino acid for rats, occurring naturally in the l(+) form. Available as glutamate and hydrochloride.

Lung inflammation and asthmaInhalation of L-arginine can increase lung inflammation and worsen asthma.Growth hormoneIntravenously-administered arginine stimulates the secretion of growth hormone , and is used in growth hormone stimulation tests. Two studies have found that oral L-arginine supplementation is also effective at increasing resting GH levels. The first study found that oral preparations of L-arginine are effective at increasing growth hormone levels. In fact, the 9g dose resulted in mean peak GH levels of 6.4 (+/- 1.3) microg / L versus placebo levels of 2.9 (+/- 0.7).MELAS syndromeSeveral trials delved into effects of L-arginine in MELAS syndrome, a mitochondrial disease.SepsisCellular arginine biosynthetic capacity determined by activity of argininosuccinate synthetase (AS) is induced by the same mediators of septic response — endotoxin and cytokines — that induce nitric oxide synthase (NOS), the enzyme responsible for nitric oxide synthesis.Malate saltThe malate salt of arginine can also be used during the treatment of alcoholic hepatitis and advanced cirrhosis.Pre-eclampsiaA preliminary study of supplementation with L-arginine and antioxidant vitamins showed that this combination may help to combat abnormally high blood pressure during high risk pregnancies.HypertensionIntravenous infusion of arginine reduces blood pressure in patients with hypertension as well as normal subjects.A recent meta-analysis showed that L-arginine reduces blood pressure with pooled estimates of 5.4 / 2.7 mmHg for SBP / DBP.Erectile dysfunctionArginine taken in combination with proanthocyanidins or yohimbine, has also been used as a treatment for erectile dysfunction.AnxietyDietary supplementation of L-arginine taken in combination with L-lysine has been shown potentially useful in treating people subjected to high levels of mental stress and anxiety, in a doubleblind, placebo controlled and randomized study, involving 108 Japanese adults. Trait anxiety and state anxiety induced by cognitive stress battery was significantly reduced, and basal levels of the stress hormone cortisol were decreased. The study was funded by Ajinomoto, Co. Inc., an industrial manufacturer of lysine and arginine.

Ammonia detoxicant; diagnostic aid (pituitary function determination).

arginine is also known as l-arginine. This is an amino acid with antistatic, masking, hair-and skin-conditioning properties.

Arginine is a nonessential amino acid that exists as white crystals or powder. it is soluble in water. it is used to improve the biological quality of the total protein in a food which contains naturally occur- ring primarily intact proteins and as a nutrient and dietary supplement.