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Home > Encyclopedia > L-Cysteine, hydrochloride, monohydrate

L-Cysteine, hydrochloride, monohydrate

pharmaceutical raw materials
L-Cysteine, hydrochloride, monohydrate structure

L-Cysteine, hydrochloride, monohydrate 

structure
  • CAS No:

    7048-04-6

  • Formula:

    C3H7NO2S.ClH.H2O

  • Chemical Name:

    L-Cysteine, hydrochloride, monohydrate

  • Synonyms:

    L-Cysteine,hydrochloride,hydrate (1:1:1);Cysteine,hydrochloride,monohydrate,L-;L-Cysteine,hydrochloride,monohydrate;Cysteine hydrochloride monohydrate;Cysteine monohydrate hydrochloride;Cysteine hydrochloride

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

Description

white crystalline powder


L-cysteine hydrochloride hydrate is a hydrate that is the monohydrate form of L-cysteine hydrochloride. It has a role as an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor, a flour treatment agent and a human metabolite. It contains a L-cysteine hydrochloride.

L-Cysteine, hydrochloride, monohydrate Basic Attributes

175.63

175.007

5158059

200-157-7

ZT934N0X4W

29309013

Characteristics

65.3

0.76610

White Solid

1.51 g/cm3

175°C

293.9ºC at 760 mmHg

131.5ºC

6 ° (C=8, 1mol/L HCl)

H2O: 1 M at 20 °C, clear, colorless

Store at RT.

<0.1 hPa (20 °C)

Safety Information

3

36/37/38

26-36

HA2285000

Xi

Stable. Incompatible with strong oxidizing agents, most common metals, hydrogen chloride.

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

|Warning|H315 (79.7%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 438 companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

L-Cysteine, hydrochloride, monohydrate Use and Manufacturing

Methods of Manufacturing

Hydrolyze the hair with hydrochloric acid for 6-8 hours, distill off the hydrochloric acid under reduced pressure, decolorize with activated carbon, and filter. The filtrate is neutralized with ammonia to obtain crude L-cystine crystals, and then recrystallized with ammonia to obtain L-cystine. Using L-cystine as raw material, L-cysteine ​​can be obtained through reduction, and there are two methods. Tin particle reduction method. Dissolve L-cystine in dilute hydrochloric acid, add tin particles and raise the temperature to reflux for 2h, filter out the remaining tin particles in the reducing solution, dilute with water, and then saturate with hydrogen sulfide; filter, and filter residue washed with a small amount of water ; Combine washing solution and filtrate, concentrate under reduced pressure, cool and crystallize, separate, and dry to obtain L-cysteine ​​hydrochloride. HOOCCH(NH2)CH2SSCH2CH(NH2)COOH+Sn[HCl, H2S→HSCH2CH(NH2)COOH·CHl electrolytic reduction method L-cystine and dilute hydrochloric acid are added to the electrolytic cell, stirred and dissolved, and electrolyzed at 50 ℃; electrolysis The solution is saturated with hydrogen sulfide for several hours; filtered, the filtrate is decolorized with activated carbon, the decolorized liquid is concentrated under reduced pressure, cooled and crystallized, separated and dried to obtain L-cysteine ​​hydrochloride, and the consumption of cystine is 0.7t per ton of product , Hydrochloric acid 1t. HOOCCH(NH2)CH2SSCH2CH(NH2)COOH+HCl→HSCH2CH(NH2)COOH·CHl

Uses

L-Cysteine is a non-essential amino acid that can be synthesized by the human body under normal physiological conditions if a sufficient quantity of methionine is available. L-Cysteine is commonly used as a precursor in the food and pharmaceutical industries. L-Cysteine is used as a processing aid for baking, as an additive in cigarettes, as well as in the preparation of meat flavours.

Cosmetics -> Antioxidant; Reducing

Computed Properties

Molecular Weight:175.64
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:175.0069920
Monoisotopic Mass:175.0069920
Topological Polar Surface Area:65.3
Heavy Atom Count:9
Complexity:75.3
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

No specific pharmacological effects are mentioned separately

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • NIPPON PROTEIN CO LTD

    United States United States
    Active
  • TAENAKA KOGYO CO LTD

    United States United States
    Active
  • Nippon Protein Co., Ltd.

    European Union European Union
    Active

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