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OXYPHENBUTAZONE HYDRATE

OXYPHENBUTAZONE HYDRATE structure

CAS No:
7081-38-1
Formula:
C19H22N2O4
Chemical Name:
OXYPHENBUTAZONE HYDRATE
Synonyms:
3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-, monohydrate;OXYPHENYL BUTAZONE MONOHYDRATE;Unii-H806S4B3ns;Oxyphenbutazone DISCONTINUED (1 g);1-(4-hydroxyphenyl)-4-(3-oxobutyl)-2-phenylpyrazolidin-3-one:hydrate;OXYPHENBUTAZONE HYDRATE;OXYPHENBUTAZONE MONOHYDRATE;OXYPHENBUTAZONE HYDRATE USP/EP/BP
Categories:
Active Pharmaceutical Ingredients > Antipyretic Analgesics

Description

ChEBI: A hydrate obtained by combining oxyphenbutazone with one molar equivalent of water. Commonly used to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Oxyphenbutazone hydrate is a hydrate obtained by combining oxyphenbutazone with one molar equivalent of water. Commonly used to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, a gout suppressant, an antipyretic, an antimicrobial agent and an antineoplastic agent. It contains an oxyphenbutazone.

OXYPHENBUTAZONE HYDRATE Basic Attributes

Molecular Weight：

342.39

Exact Mass：

342.15800

Color/Form：

White to Off-White

Characteristics

PSA：

70.08000

XLogP3：

3.55910

Melting Point：

96°; mp 124-125°

Boiling Point：

485.6ºC at 760 mmHg

Flash Point：

247.5ºC

Storage Conditions：

2-8°C

Critical Temperature & Pressure：

2-8°C

Safety Information

hazard class code：

safety instructions：

22-26-36

Marks：

Hazard Statements：

22-36/38-40-42/43

OXYPHENBUTAZONE HYDRATE Use and Manufacturing

Antiinflammatory; antirheumatic.

Computed Properties

Molecular Weight:342.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:342.15795719
Monoisotopic Mass:342.15795719
Topological Polar Surface Area:61.8
Heavy Atom Count:25
Complexity:454
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes