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Oxyphenbutazone monohydrate

Oxyphenbutazone monohydrate structure

Oxyphenbutazone monohydrate 

structure
  • CAS No:

    7081-38-1

  • Formula:

    C19H20N2O3.H2O

  • Chemical Name:

    Oxyphenbutazone monohydrate

  • Synonyms:

    3,5-Pyrazolidinedione,4-butyl-1-(4-hydroxyphenyl)-2-phenyl-,hydrate (1:1);3,5-Pyrazolidinedione,4-butyl-1-(p-hydroxyphenyl)-2-phenyl-,monohydrate;3,5-Pyrazolidinedione,4-butyl-1-(4-hydroxyphenyl)-2-phenyl-,monohydrate;1-(p-Hydroxyphenyl)-2-phenyl-4-butyl-3,5-pyrazolidinedione monohydrate;Oxyphenbutazone monohydrate;Tandearil monohydrate;76576-51-7

  • Categories:

    Active Pharmaceutical Ingredients  >  Antipyretic Analgesics

Description

ChEBI: A hydrate obtained by combining oxyphenbutazone with one molar equivalent of water. Commonly used to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.


Oxyphenbutazone hydrate is a hydrate obtained by combining oxyphenbutazone with one molar equivalent of water. Commonly used to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, a gout suppressant, an antipyretic, an antimicrobial agent and an antineoplastic agent. It contains an oxyphenbutazone.

Oxyphenbutazone monohydrate Basic Attributes

342.39

342.15800

Characteristics

70.08000

3.55910

96 °C

485.6ºC at 760 mmHg

247.5ºC

2-8°C

Safety Information

22-36/38-40-42/43

22-26-36

Xn

Oxyphenbutazone monohydrate Use and Manufacturing

Antiinflammatory; antirheumatic.

Computed Properties

Molecular Weight:342.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:342.15795719
Monoisotopic Mass:342.15795719
Topological Polar Surface Area:61.8
Heavy Atom Count:25
Complexity:454
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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