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Biperiden lactate

Biperiden lactate structure

CAS No:
7085-45-2
Formula:
C21H29NO.C3H6O3
Chemical Name:
Biperiden lactate
Synonyms:
Propanoic acid,2-hydroxy-,compd. with α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-1-piperidinepropanol (1:1);Lactic acid,compd. with α-5-norbornen-2-yl-α-phenyl-1-piperidinepropanol (1:1);1-Piperidinepropanol,α-5-norbornen-2-yl-α-phenyl-,lactate;1-Piperidinepropanol,α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-,2-hydroxypropanoate (salt);Akineton lactate;α-(Bicyclo[2.2.1]hept-5-en-2-yl)-α-phenyl-1-piperidine propanol lactate;Biperiden lactate;1334-00-5
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

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Biperiden lactate Basic Attributes

Molecular Weight：

383.52

Exact Mass：

401.25700

EC Number：

230-388-9

UNII：

09TD6C5147

Characteristics

PSA：

81.00000

XLogP3：

3.35210

Melting Point：

101 deg C

Boiling Point：

462.1ºC at 760mmHg

Flash Point：

224.5ºC

Water Solubility：

In water, 25.1 mg/L at 25 deg C (est)

Storage Conditions：

Biperiden hydrochloride tablets should be stored in tight, light-resistant containers at 15-30 deg C.

Vapor Pressure：

5.42 mm Hg at 25 deg C (est)

Drug Information

MeSH：

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)|Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)|Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)

MeSH Entry Terms：

biperiden lactate

Biperiden lactate Use and Manufacturing

Uses

Anticholinergic; antiparkinsonian.

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:401.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:401.25660860
Monoisotopic Mass:401.25660860
Topological Polar Surface Area:81
Heavy Atom Count:29
Complexity:481
Undefined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes