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trans-Chalcone oxide

trans-Chalcone oxide structure

trans-Chalcone oxide 

structure
  • CAS No:

    7570-86-7

  • Formula:

    C15H12O2

  • Chemical Name:

    trans-Chalcone oxide

  • Synonyms:

    Methanone,phenyl[(2R,3S)-3-phenyl-2-oxiranyl]-,rel-;Propiophenone,2,3-epoxy-3-phenyl-,trans-;Methanone,phenyl(3-phenyloxiranyl)-,trans-;Methanone,phenyl[(2R,3S)-3-phenyloxiranyl]-,rel-;rel-Phenyl[(2R,3S)-3-phenyl-2-oxiranyl]methanone;trans-Chalcone oxide;trans-1,3-Diphenyl-1,2-epoxy-3-propanone;trans-2-Benzoyl-3-phenyloxirane;trans-Epoxy-1-phenyl-3-phenylpropane-3-one;rel-Phenyl[(2R,3S)-3-phenyloxiranyl]methanone;trans-2,3-Epoxy-1,3-diphenyl-1-propanone;trans-1,3-Diphenyl-2,3-epoxyprop-1-one;(Phenyl)(trans-3-phenyloxiranyl)methanone;NSC 402160;67381-79-7

trans-Chalcone oxide Basic Attributes

224.25500

224.25

DTXSID90352520

Characteristics

29.60000

3.00940

1.209g/cm3

77-83 °C @ Solvent: Ethanol

374.1ºC at 760 mmHg

174ºC

1.617

Safety Information

NONH for all modes of transport

3

22-24/25

UH1589300

trans-Chalcone oxide Use and Manufacturing

trans-Chalcone oxide is an alpha, beta unsaturated ketone that comes from nature and can also be synthesized in the laboratory. Trans-oxide chalcone is usually solid at room temperature. It can be cross-linked with the peroxide and maintains its original shape through chemical cross-linking and crystalline regions. It can undergo elastic deformation and return to its original shape after heating. trans-Chalcone oxide, a derivative of Chalcone, is used in pharmaceutical, agricultural and materials science, and a number of other applications are under investigation. Firstly, trans-Chalcone oxide is used in the pharmaceutical field because of its good biological activity. It has a powerful effect of promoting cancer cell apoptosis, programmed cell death, inhibiting cancer cell proliferation, and inhibiting tumor growth, so relevant personnel will conduct in-depth research on it as an anticancer drug, and it is expected to become a clinical drug in the future. In addition, anti-inflammatory properties of trans-Chalcone oxide are also being investigated. trans-Chalcone oxide is used in agriculture because of its insecticidal properties. Because it is available in nature and biodegradable, it is also expected to be developed as an environmentally friendly pesticide and an alternative to traditional pesticides in the future, thereby reducing environmental harm and promoting sustainable development in the field of chemistry. This substance can also be used to synthesize polymers, or as a precursor for advanced materials, which can be added to mechanical, transparent and other materials to change the overall material properties.

Computed Properties

Molecular Weight:224.25
XLogP3:2.8
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:224.083729621
Monoisotopic Mass:224.083729621
Topological Polar Surface Area:29.6
Heavy Atom Count:17
Complexity:275
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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