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Home > Encyclopedia > 2-(2-Hydroxyethyl)phenol

2-(2-Hydroxyethyl)phenol

2-(2-Hydroxyethyl)phenol structure

2-(2-Hydroxyethyl)phenol 

structure
  • CAS No:

    7768-28-7

  • Formula:

    C8H10O2

  • Chemical Name:

    2-(2-Hydroxyethyl)phenol

  • Synonyms:

    Benzeneethanol,2-hydroxy-;Phenethyl alcohol,o-hydroxy-;2-Hydroxybenzeneethanol;2-(o-Hydroxyphenyl)ethanol;β-(o-Hydroxyphenyl)ethanol;o-Hydroxyphenethyl alcohol;2-(2-Hydroxyphenyl)ethanol;o-(2-Hydroxyethyl)phenol;2-(2-Hydroxyethyl)phenol;2-Hydroxyphenethyl alcohol;1,2-Tyrosol;2-(2-Hydroxyphenyl)ethyl alcohol;NSC 101845;6-(2-Hydroxyethyl)phenol

Description

Clear yellow liquid


2-(2-hydroxyphenyl)ethanol is a phenol that is 2-phenylethanol in which the phenyl ring is substituted at position 2 by a hydroxy group. It has a role as a metabolite. It derives from a 2-phenylethanol.

2-(2-Hydroxyethyl)phenol Basic Attributes

138.16

138.16

231-863-3

C6AV79GN9F

101845

DTXSID90228312

2907299090

Characteristics

40.5

1.2

1.2±0.1 g/cm3

110 °C @ Press: 0.55 Torr

132.8±15.0 °C

1.578

Safety Information

NONH for all modes of transport

2

22-41-36/37/38

S26-S36-S37-S39

Xn,Xi

P280-P305 + P351 + P338

H302-H318

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501|Aggregated GHS information provided by 41 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

2-hydroxyphenylethanol

2-(2-Hydroxyethyl)phenol Use and Manufacturing

Preparation 17a: 2-(2-phenylmethoxyphenyl)ethanol[00177] A mixture of 2-(2-hydroxyethyl)phenol (lg, 7.2 mmol), bromomethylbenzene (1.35 g, 7.92 mmol) and K2C03(2 g, 14.5 mmol) was stirred overnight at 90 °C. H20 was added, extracted with ethylacetate, purified by flash column chromatography on silica gel (PE/EA=1/1) to afford the title compound (1.48 g, 90percent). [M+H] Calc'd for Ci5Hi602, 229; Found, 229.(1) 2-(2-Benzyloxyphenyl)ethanol To a solution of sodium ethoxide (10.8 g) in ethanol (500 ml),

Computed Properties

Molecular Weight:138.16
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:138.068079557
Monoisotopic Mass:138.068079557
Topological Polar Surface Area:40.5
Heavy Atom Count:10
Complexity:93.3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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