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Home > Encyclopedia > Ethanone, 1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:1)

Ethanone, 1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:1)

Ethanone, 1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:1) structure

Ethanone, 1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:1) 

structure
  • CAS No:

    7455-18-7

  • Formula:

    C19H22N2OS.C4H4O4

  • Chemical Name:

    Ethanone, 1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:1)

  • Synonyms:

    Ethanone,1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-,(2Z)-2-butenedioate (1:1);Ketone,10-[2-(dimethylamino)propyl]phenothiazin-2-yl methyl,maleate (1:1);Ethanone,1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-,(Z)-2-butenedioate (1:1);Ketone,10-[2-(dimethylamino)propyl]phenothiazin-2-yl methyl,maleate

Ethanone, 1-[10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:1) Basic Attributes

442.52794

442.156243

231-228-0

Characteristics

132

121-122 °C

Safety Information

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P272, P273, P280, P301+P312, P302+P352, P305+P351+P338, P310, P321, P330, P333+P313, P363, P391, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)|Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)

aceprometazine

Computed Properties

Molecular Weight:442.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:442.15624311
Monoisotopic Mass:442.15624311
Topological Polar Surface Area:132
Heavy Atom Count:31
Complexity:536
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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