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Sanguinarine hydrochloride

Sanguinarine hydrochloride structure

CAS No:
5578-73-4
Formula:
C20H14NO4.Cl
Chemical Name:
Sanguinarine hydrochloride
Synonyms:
[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-,chloride (1:1);Sanguinarine,chloride;[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-,chloride;Sanguinarine hydrochloride;13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride;Sanguinarium chloride
Categories:
Natural Products > Alkaloids

Description

Sanguinarine chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

Sanguinarine hydrochloride Basic Attributes

Molecular Weight：

367.78

Exact Mass：

367.061127

UNII：

B8Z8J4400H

HScode：

29399990

Characteristics

PSA：

40.80000

XLogP3：

0.43210

Melting Point：

287-289 °C

Water Solubility：

methanol: 20 mg/mL, clear, orange

Storage Conditions：

Store at +4°C

Safety Information

wgk germany：

hazard class code：

safety instructions：

36-26

RTECS Number：

VP5220000

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 41 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)|Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)

MeSH Entry Terms：

pseudo-chelerythrine

Sanguinarine hydrochloride Use and Manufacturing

antineoplastic, antiplaque agent

Computed Properties

Molecular Weight:367.8
Hydrogen Bond Acceptor Count:5
Exact Mass:367.0611356
Monoisotopic Mass:367.0611356
Topological Polar Surface Area:40.8
Heavy Atom Count:26
Complexity:530
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Sanguinarine hydrochloride

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SANGUINARINE CHLORIDE

CAS No.: 5578-73-4

Content: 99.00%

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Manufactory Supplier of Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5,Ginsenoside Rg5,Ginsenoside Rh2,Protopanaxatriol,Epmedin C,Icariin,Icaritin,Baohuoside I,Total Ginsenosides,Total Ginsenosides from Ginseng Stems And Leaves,Oridonin,Oleuropein,Curcumin,(20)-Ginsenoside Rg3,(20)-Protopanaxadiol

SANGUINARINE CHLORIDE

Unit Price: $250-260 /G EXW

CAS No.: 5578-73-4

Grade: Industrial Grade

Content: 98%

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Guide of Sanguinarine hydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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