Zinc fluoride

103.39

101.92600

232-001-9

3077

COLORLESS MONOCLINIC OR TRICLINIC CRYSTALS|TETRAGONAL NEEDLES (RUTILE LATTICE) OR WHITE CRYSTALLINE MASS

28261990

0

0.83790

White to beige to light brown powder

4.9 g/cm³

872 °C

1500 °C

1500°C

H2O: SLIGHTLY soluble ;Sparingly soluble in hydrochloric acid, nitric acid, and ammonium hydroxide.

MAY BE STORED IN GLASS BOTTLES. /TETRAHYDRATE/

1 mm Hg ( 970 °C)

Subcutaneous-Frog LDL0: 280 mg/kg

Non-combustible; emits toxic hydrogen fluoride gas in case of acid; generates toxic fluoride smoke when heated

Heat of soln= -227.8 Btu/lb= -126.5 cal/g= -5.3X10+5 J/kg|COLORLESS, RHOMBOHEDRAL CRYSTALS; DENSITY: 2.255 SOL IN AMMONIUM HYDROXIDE, ACIDS & ALKALI; 3000 °C IS TRANSITION POINT TO ZNO (ZINC NITRIC OXIDE) /TETRAHYDRATE/

Slightly soluble in water.

Salts, Basic

ZINC FLUORIDE can react violently with potassium [Hawley]. Fluorinates organic compounds. Soluble in hot acids. Solutions of zinc fluoride may contain some hydrofluoric acid, which can cause severe chemical burns and is one of the few materials that can etch glass. Unlike other halide ions, fluoride is quite reactive, acting as a weak base and participating in some unique reactions. In particular, fluorides react strongly with compounds containing calcium, magnesium, or silicon ions, which means that solutions containing soluble fluorides are corrosive to both living tissue and glass.

958.4 Btu/lb= 532.5 cal/g= 22.3X10+5 J/kg (Est at BP 1500 °C)

III

6.1

3288

3

37/38-41-36/37/38-23/24/25

26-39-37/39-45-36/37/39-28

ZH3500000

Xi,T

The warehouse is ventilated, low temperature and dry; stored separately from acids and food additives

Toxic

hygroscopic

P280-P305 + P351 + P338 + P310

H315-H318-H335

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Reacts violently with potassium.|Mixture of potassium and zinc fluoride produces a weak explosion on impact.

A review with 100 references on the synergistic antiplaque effects of zinc fluoride-hexetidine mouthwashes.[Saxer UP, Muehlemann HR; Synergistic Antiplaque Effects of a Zinc Fluoride/Hexetidine Containing Mouthwash. A Review; Schweiz Monatsschr Zakjnheilkd 93 (8): 689-704 (1983)]|Zinc and Health. Current Bibliographies in Medicine 98-3. Public Services Division/National Library of Medicine. 3619 citations, January, 1990-June, 1998.[Available from, as of November 2, 1998: http://www.nlm.nih.gov/archive/20040831/pubs/cbm/zinc.html]|USEPA; Ambient Water Quality Criteria Doc: Zinc (1980) EPA 400/5-80-079|USEPA; Ambient Water Quality Criteria Doc: Zinc (1987) EPA 400/5-87-003|For more Special Reports (Complete) data for ZINC FLUORIDE (7 total), please visit the HSDB record page.

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state. (ERG, 2016)

|Danger|H301 (16.98%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 53 companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H320: Causes eye irritation [Warning Serious eye damage/eye irritation]|P260, P261, P264, P270, P271, P304+P340, P305+P351+P338, P312, P314, P337+P313, P403+P233, P405, and P501

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent dust cloud. Avoid inhalation of asbestos dust. SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area. SMALL SPILL: Pick up with sand or other non-combustible absorbent material and place into containers for later disposal. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Cover powder spill with plastic sheet or tarp to minimize spreading. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2016)

Approved dust and fume respirator, skin and eye protection. (USCG, 1999)|Workers handling dangerous substances should be supplied with eye and face protection, respiratory protective equipment, protective clothing and foot and leg protection. Additional protection may be provided by the use of lanolin as a barrier cream. /Fluorine and cmpd/

Non-combustible

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty.

Environmental considerations: Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be contained with a flexible impermeable membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.|Environmental considerations: Water spill: Neutralize with agricultural lime (CaO), crushed limestone, or sodium bicarbonate. Add soda ash. Adjust pH to neutral (pH 7). Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates or greater concentration.

If material not on fire and not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Keep upwind. Avoid breathing vapors or dusts. Wash away any material which may have contacted the body with copious amounts of water or soap and water.|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|... Concn of fluorine and its cmpd should not exceed the recommended max permissible levels. Processes in which there is a potential exposure hazard should be equipped with local exhaust ventilation and should ... be mechanized. ... Workers should not consume food or beverages in the workplace and rigorous personal hygiene should be observed before meals are taken. /Fluorine and cmpd/

Irritating to eyes and nose.

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 2.5 mg/cu m. /Fluorides as F/|Permissible Exposure Limit: Table Z-2 8-hr Time Weighted Avg: 2.5 mg/cu m. /Fluoride as dust/

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

highly toxic

Patients with kidney dysfunction may be particularly susceptible to fluoride toxicity. /Fluoride/

Food and Environmental Agents: Effect on Breast-Feeding: Reported Sign or Symptom in Infant or Effect on Lactation: Fluorides: None. /from Table 7/

LETHAL DOSE FOR MAN OF SOL FLUORIDES WAS EST AT ... 2.5 G. ... INGESTION OF AS LITTLE AS 9 MG/KG HAS CAUSED HUMAN DEATHS. /FLUORIDES/

FLUORIDES ARE ABSORBED FROM GI TRACT, LUNG, & SKIN. GI TRACT IS MAJOR SITE OF ABSORPTION. DEGREE OF ABSORPTION ... IS BEST CORRELATED WITH ITS SOLUBILITY. RELATIVELY SOL CMPD ... ARE ALMOST COMPLETELY ABSORBED ... SECOND MOST COMMON ROUTE OF ABSORPTION IS BY ... LUNG. ... THIRD, & RELATIVELY RARE, ROUTE ... IS THROUGH THE SKIN. FLUORIDE HAS BEEN DETECTED IN ALL ORGANS & TISSUES EXAM AND IT IS CONCN IN EXCEPT BONE, THYROID, AORTA, & PERHAPS KIDNEY. ... /IT/ IS PREPONDERANTLY DEPOSITED IN SKELETON & TEETH, & THE SKELETAL BURDEN IS RELATED TO INTAKE & AGE. ... MAJOR ROUTE OF FLUORIDE EXCRETION IS BY ... KIDNEYS; HOWEVER SMALL AMOUNTS OF FLUORIDE APPEAR IN SWEAT, MILK AND INTESTINAL SECRETIONS... ABOUT 90% OF FLUORIDE FILTERED BY GLOMERULUS IS REABSORBED BY RENAL TUBULES. /FLUORIDES/|Upon intravenous injection zinc is distributed to erythrocytes, plasma, and leukocytes; about 80% of the zinc present in the blood is found in the erythrocytes, 12-20% in the plasma, and about 3% in the leukocytes. ... There is a dynamic exchange of zinc between plasma and erythrocytes. Inhalation of dusts of zinc salts results in a transient accumulation in the lung before its absorption into the blood. There is little absorption of zinc or its salts through the skin. ... About 80% of parenterally administered zinc is excreted in the feces, suggesting an enterohepatic circulation for zinc. In humans, about 10% of the absorbed zinc is excreted in the urine, and in tropical climates about 2-3 mg zinc/day may be lost in sweat. /Soluble zinc compounds/

... Fluoride interacts with bones and teeth by replacing hydroxyl or bicarbonate ions in hydroxyapatite to form fluorohydroxyapatite. ... The presence of fluorohydroxyapatite increases the crystalline structure of the bone and reduces its solubility. ... Dental fluorosis results from toxic effects of fluoride on the epithelial enamel organ. /Fluoride/|In acute poisoning, fluoride kills by blocking normal cellular metabolism. Fluoride inhibits enzymes, in particular metalloenzymes involved in essential processes, causing vital functions such as the initiation and transmission of nerve impulses, to cease. ... /Fluoride/

INHALATION: Irritation of nasal passages, dryness, and nose bleed. EYES: Irritation may occur. SKIN: Excessive exposure may cause a rash. INGESTION: Salty or soapy taste, salivation, nausea, burning or crampy abdominal pain, vomiting, diarrhea, dehydration, and thirst. (USCG, 1999)

Call a physician. INHALATION: Remove from exposure. EYES: Flush with water. SKIN: Wash with soap and cold water. INGESTION: Gastric lavage with lime water or a 1% solution of calcium chloride. Give several ounces of lime water at frequent intervals. Milk may be substituted. Aluminum hydroxide gel may be used to bind fluoride. (USCG, 1999)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Fluorine and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's to support vital signs if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Fluorine and related compounds/

SYMPTOMATOLOGY: 1. Severe gastritis or gastroenteritis with abdominal pain, retching, and prolonged vomiting, beginning 10-60 min after ingestion. Vomitus may become bloody. Diarrhea is sometimes violent; the feces are watery and later tarry. Dehydration becomes intense. 2. Shock, pallor, cyanosis and coldness. Rapid, weak or imperceptible pulse, low blood pressure, rapid and shallow respirations. 3. Sometimes breathing is deep and rapid, reflecting an accompanying metabolic acidosis. 4. Drowsiness, hyporeflexia, dilated pupils, coma. Vasomotor instability, shock or coma and a serum iron level in great excess of the total iron-binding capacity are poor prognostic signs. /Fluoride/|SYMPTOMATOLOGY: 5. Liver injury, consisting of hemorrhagic necrosis which is usually reversible. 6. Death from shock, usually in 4-5 hr. Sometimes following apparent recovery, pneumonia with fever or secondary shock may cause death 1-3 days later. 7. Among survivors pyloric stenosis and mild hepatic cirrhosis may be encountered as persistent sequelae, but recovery is usually complete. /Fluoride/|Initial symptoms from ingestion /include/ ... salivation, nausea, abdominal pain, vomiting, and diarrhea. ... The patient shows signs of increased irritability of the nervous system, including paresthesias, a positive Chvostek sign, hyperactive reflexes, and tonic and clonic convulsions. ... Hypocalcemia and hypoglycemia are frequent lab findings. ... Pain in various muscle groups ... blood pressure falls ... due to central vasomotor depression as well as direct toxic action on cardiac muscle. The respiratory center is first stimulated and later depressed. Death ... from either respiratory paralysis or cardiac failure. /Fluoride salts/|... THE MAJOR MANIFESTATIONS OF CHRONIC INGESTION OF EXCESSIVE AMT OF FLUORIDE ARE OSTEOSCLEROSIS & MOTTLED ENAMEL. CHRONIC EXPOSURE TO EXCESS FLUORIDE CAUSES INCR OSTEOBLASTIC ACTIVITY. ... DENSITY AND CALCIFICATION OF BONE ARE INCR ... THOUGHT TO REPRESENT THE REPLACEMENT OF HYDROXYAPATITE BY THE DENSER FLUOROAPATITE. /FLUORIDE SALTS/|For more Human Toxicity Excerpts (Complete) data for ZINC FLUORIDE (8 total), please visit the HSDB record page.

zinc fluoride

GRADE: TECHNICAL, ABOUT 95% PURE|COMMERCIAL: (CALCULATED) 96%|4 Mesh, 99 & 99.5% purity grades

ZINC FLUORIDE USED FOR FLUORINATIONS SHOULD BE SLIGHTLY HYDRATED.|Dental plaque inhibition was demonstrated in rats and humans by using zinc fluoride hexetidine combination in a mouthwash.