Sodium aluminum phosphate
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Sodium aluminum phosphate
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CAS No:
7785-88-8
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Formula:
Al.xH3O4P.xNa
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Chemical Name:
Sodium aluminum phosphate
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Synonyms:
Phosphoric acid,aluminum sodium salt (1:?:?);Phosphoric acid,aluminum sodium salt;Sodium aluminum phosphate;Aluminum sodium phosphate;Sodium aluminum orthophosphate;E 541;Budal 2308;Sodium aluminium phosphate;12764-58-8
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CAS No:
Characteristics
192.12000
1.10950
White powder. Odorless.
158ºC at 760 mmHg
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition so
VERY BLAND
White powder; odorless. Insoluble in water; soluble in hydrochloric acid /Tetrahydrate/
Safety Information
Very stable in presence of moisture /sodium aluminum phosphate compounds/
Aluminum compounds are treated under anhydrous conditions to prevent violent reactions, recover solvent, and form Al compounds suitable for landfill by reaction with anhydrous hydrolysis agent, eg calcium hydroxide. /Aluminum compounds/|SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
Extremely reactive with air, moisture, and compounds containing active hydrogen... /Alkyl aluminum compounds/|Reacts violently with a broad range of materials including air & water. /Aluminum alkyls/
Sodium aluminum phosphate used for multiple purposes in food for human consumption is generally recognized as safe when used in accordance with good manufacturing practice.|Sodium aluminum phosphate used as a general purpose food additive in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
|Danger|H315 (62.5%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 18 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Wear appropriate personal protective clothing to prevent skin contact. /Aluminum (soluble salts and alkyls, as Al/|Wear appropriate eye protection to prevent eye contact. /Aluminum (soluble salts and alkyls, as Al)/|Protective clothing and a high standard of training in the necessary precautionary measures are essential for the handling of the materials. /Aluminum alkyls/
Certain polymerization catalysts, such as aluminum alkyls, react & burn violently on contact with water. /Aluminum alkyls/|Aluminum alkyls are organic aluminum compounds that are highly reactive and dangerous because of spontaneous burning in air. /Aluminum alkyls/|Prophoric material in flammable solvent. Vapors are heavier than air & may travel to a source of ignition & flash back. /Aluminum alkyls/
...Violently explosive when they come into contact with water. /Aluminum alkyls/
Stop flow of liquid before extinguishing fire. Use dry chemical or carbon dioxide. DO NOT use water as straight stream directly on spilled material. Water fog can be used to control fire. DO NOT use halogenated extinguishing agents on spilled material. Violent reaction may result. Use water spray to keep fire-exposed containers cool. Fight fire from protected location or maximum possible distance. /Aluminum Alkyls/
SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|Work clothing that becomes wet or significantly contaminated should be removed and replaced. /Aluminum (soluble salts and alkyls, as Al)/|Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises. /Aluminum (soluble salts and alkyls, as Al)/|The worker should immediately wash the skin when it becomes contaminated. /Aluminum (soluble salts and alkyls, as Al)/|SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.
The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./
/Aluminum (dust or powder)/ may cause minor irritation to lungs & eyes. /Aluminum powder, uncoated/|Irritation of the eyes has been noted in patients who have been exposed /to aluminum alkyls/. /Aluminum alkyls/|May cause minor irritation to lungs or eyes. /Aluminum (dust or powder)/
Recommended Exposure Limit: 10-Hr Time-Weighted Avg: 10 mg/cu m (total). /Aluminum/|Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 5 mg/cu m (resp). /Aluminum/|Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 2 mg/cu m. /Aluminum (soluble salts and alkyls, as Al)/|Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 5 mg/cu m. /Aluminum (pyro powders and welding fumes, as Al)/
Toxicity
In the gut, antacids form insoluble compounds with numerous substances. Interactions are especially prominent with aluminum-containing antacids. Aluminum forms insoluble aluminum phosphate, which decreases the bioavailability of phosphate. Although aluminum fluoride is somewhat soluble, aluminum-containing antacids interfere with the absorption of fluoride, probably through the formation of more complex compounds, such as fluoroapatite. Aluminum-containing antacids adsorb bile acids, lysolecithin, and various proteins. /Aluminum-Containing antacids/
... IT IS A SUBSTANCE WHICH MIGRATES TO FOOD FROM PACKAGING MATERIALS. /NA3PO4.ALPO4/
Drug Information
/Aluminum sodium sulfate is used in/ medicine.
Aluminum phosphate mixture is a slow acting antacid used similarly to aluminum hydroxide mixture. Unlike aluminum hydroxide, it does not interfere with phosphate absorption and is used when a high-phosphporus diet cannot be maintained or if there is diarrhea or a deficiency of pancreatic juice. It is also used as an adjuvant in adsorbed vaccines. The mixture is given in doses of 5 to 15 ml and dried aluminum phosphate in doses of 400 to 800 mg. /Aluminum hydroxide/
Men were fed biscuits containing alum phosphate baking powder (about 8%) in addition to normal dietary items, and blood and urine samples collected two, four, six and eight hours after the meal. Aluminium was frequently found in blood of control men (trace - 0.1 mg/100 mL), and ingestion of the aluminium rich diet caused occasional slight increase of levels of aluminium in the blood. Urine of man before and after ingestion of the aluminium rich diets only contain small amounts of aluminium (<0.5 mg excreted in 26 hours).
Treatment: to relieve the GI distress /caused by swallowing aluminum salts/... The degree of dehydration and electrolyte loss caused by vomiting and diarrhea must be determined, and corrected by iv infusions of appropriate solutions. /Aluminum salts/|Diagnosis: when history is unattainable, diagnosis depends on the demonstration of large amount of aluminum in vomitus, stomach contents or feces. /aluminum compounds/|Deferoxamine has been used to treat dialysis encephalopathy and osteomalacia with symptomatic relief reported. The use of deferoxamine for aluminum-toxic dialysis patients has been suggested for serum levels of aluminum between 100 and 200 ug/mL. Deferoxamine also has been used to diagnose aluminum-related osteodystrophy. After a deferoxamine infusion of 40 mg/kg over 2 hours, an increment in plasma aluminum concentration of 200 ug/L identified 35 of 37 patients with biopsy-proven aluminum-related osteodystrophy (sensitivity, 94%; specificity, 50%). Calcium disodium ethylenediaminetetraacetic acid does not appear as effective as deferoxamine in chelating aluminum. Especially in dialysis patients, aluminum-containing medications should be reduced. //al/
aluminum sodium phosphate
Sodium aluminum phosphate Use and Manufacturing
Reaction of hydrated alumina and sodium carbonate or hydroxide with phosphoric acid.
Leavening agent in baked goods (acidic grade), emulsifier in processed cheese (basic grade).
(1972) 1.1X10+10 GRAMS (EST)|(1973) 2.6X10+10 G (CONSUMPTION)
71% AS A LEAVENING AGENT IN BAKED GOODS; 29% AS AN EMULSIFIER IN PROCESSED CHEESE (1973)
Grades: Technical; FCC /food chemicals codex/|The most common blend of leavening acids is 20-30% monocalcium phosphate monohydrate or anhydrous monocalcium phosphate and 70-80% sodium aluminum phosphate.
Phosphoric acid, aluminum sodium salt (1:?:?): ACTIVE|Formulas for baking powders containing sodium aluminum phosphates have been proposed, but they have not been accepted by the industry to any extent.
Computed Properties
Molecular Weight:144.943
Hydrogen Bond Acceptor Count:4
Exact Mass:144.9247282
Monoisotopic Mass:144.9247282
Topological Polar Surface Area:86.2
Heavy Atom Count:7
Formal Charge:1
Complexity:36.8
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
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