Bromine pentafluoride

174.9

174.90

232-157-8

UPI6B7Y9UQ

0974

1745

Liquid|Colorless fuming liquid

0

2.94660

Bromine pentafluoride appears as a colorless, fuming liquid with a pungent odor. Used to make other chemicals and in rockets. Very toxic by inhalation. Corrosive to metals and tissue. Will accelerate the burning of combustible material. If the containers are involved in a fire they may rupture violently and rocket.

2.4604 g/cm³ @ Temp: 25 °C

-60.5 °C

40.76 °C

Index of refraction: 1.3529

H2O: Insoluble

Separate from acids, alkalies, halogens, salts, metals, organic matter. Store in a cool, dry, well-ventilated location. Keep cylinders restrained ...

328 mmHg

Relative vapour density (air = 1): 6.1

Decomposes highly toxic hydrogen fluoride in case of water and moisture; flammable in case of organic matter; emits bromine and fluorine gas in case of heat and acid

Pungent odor

Fumes in air. Thermostable up to 460 °C. Very reactive, usually with conflagration. Produces an explosion on contact with water. Does not attack quartz when dry.|An extremely vigorous fluorinating agent. Will react with water or steam to produce toxic and corrosive fumes. Explodes or ignites on contact with hydrogen-containing materials (e.g. acetic acid, ammonia, benzene, ethanol, hydrogen, hydrogen sulfide, methane cork, grease, paper, wax, chloromethane).|Reacts with every known element except inert gases, nitrogen, and oxygen|Explodes on contact with water. Products of this rapid reaction include HF and possibly Br2 ... is decomposed exothermically by water to hydrofluoric acid and other materials.

Produces corrosive fumes in moist air. Reacts explosively upon contact with water. Very reactive, usually with conflagration [Merck, 11th ed. 1989]. Reaction with water is violent, oxygen being evolved, [Mellor 2 Supp. 1:172 1956]. Explodes on contact with water. Products of this rapid reaction include HF and possibly Br2 (Lewis 2000). HBr gas might also be produced upon reaction with water. Based on a scenario where the chemical is spilled into an excess of water (at least 5 fold excess of water), half of the maximum theoretical yield of Hydrogen Fluoride (hydrofluoric acid) gas will be created in 1.2 minutes. Experimental details are in the following: "Development of the Table of Initial Isolation and Protective Distances for the 2008 Emergency Response Guidebook", ANL/DIS-09-2, D.F. Brown, H.M. Hartmann, W.A. Freeman, and W.D. Haney, Argonne National Laboratory, Argonne, Illinois, June 2009.

Oxidizing Agents, Strong

Strong Oxidizing Agent

BROMINE PENTAFLUORIDE an oxidizing agent. Is decomposed exothermically by water to hydrofluoric acid and other materials. Reacts with these other hydrogen-containing substances (among others) vigorously enough to cause a fire or explosion: acetic acid, ammonia, benzene, ethanol, hydrogen, hydrogen sulfide, methane, cork, grease paper, wax. Mixtures with acids, halogens, metal halides, metals, nonmetals, or metal oxides at ambient or slightly above ambient temperatures have resulted in violent reaction (nitric acid, sulfuric acid, chlorine, iodine, ammonium chloride, potassium iodide, boron powder, selenium, tellurium, aluminum powder, bismuth, cobalt powder, iron powder, arsenic, nickel powder, chromium trioxide, charcoal, red phosphorus, sulfur dioxide, magnesium oxide. Solutions of acetonitrile and 9% bromine pentafluoride have been found to decompose violently at ambient temperatures. Mixtures of perchloryl perchlorate and bromine pentafluoride form shock sensitive explosives. [Bretherick, 5th ed., 1995, p. 640].

Noncombustible Liquid, but a very powerful oxidizer.

The vapour is heavier than air.

30.6 kJ/mol at 297-314 deg K, 31.2 kJ/mol at 213-297 deg K

I

5.1

1745

8-23/24/25-34

7/8-36/37/39-45

O

The warehouse is ventilated, low temperature and dry; stored separately from fuel and organic matter

Oxidising agent

Strong oxidizing agent. Reacts with water, combustible materials, acids, metals. Explosion risk.

P210, P220, P221, P260, P264, P270, P271, P280, P283, P284, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P306+P360, P307+P311, P309+P311, P310, P314, P320, P321, P331, P363, P370+P378, P371+P380+P375, P403+P233, P405, P501

H271

SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.|SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

Acids, halogens, arsenic, selenium, sulfur, glass, organic materials, water [Note: Reacts with all elements except inert gases, nitrogen and oxygen.]|Although soln of bromine pentafluoride in acetonitrile were reported stable at ambient temp, it has been found that a 9% soln in the anhydrous solvent prepared at -196 °C decomp violently, bursting the container, about 1 hr after attaining ambient temp.|Contact /of bromine pentafluoride/ with the following at ambient or slightly elevated temp is violent, ignition often occurring: strong nitric acid or sulfuric acids; chlorine (explodes on heating), iodine; ammonium chloride, potassium iodide; antimony, arsenic, boron powder, selenium, tellurium; aluminium powder, barium, bismuth, cobalt powder, chromium, iridium powder, iron powder, lithium powder, manganese, molybdenum, nickel powder, rhodium powder, tungsten, zinc; charcoal, red phosphorus, sulfur, arsenic pentoxide, boron trioxide, calcium oxide, carbon monoxide, chromium trioxide, iodine pentoxide, magnesium oxide, molybdenum trioxide, phosphorus pentoxide, sulfur dioxide or tungsten trioxide.|Contact /of bromine pentafluoride/ with the following materials, containing combined hydrogen, is likely to cause fire or explosion: acetic acid, ammonia, benzene, ethanol, hydrogen, hydrogen sulfide, methane; cork, grease, paper, wax, etc. The carbon content further contributes to the observed reactivity. Chloromethane react with explosive violence.|For more Hazardous Reactivities and Incompatibilities (Complete) data for BROMINE PENTAFLUORIDE (7 total), please visit the HSDB record page.

National Academy of Sciences; Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 18 (2014)

Special Hazards of Combustion Products: Toxic and irritating fumes of hydrogen fluoride and bromine may form in fires. Behavior in Fire: Containers may burst when exposed to heat of fire. (USCG, 1999)|Not combustible but enhances combustion of other substances. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion on contact with water, steam, fuels or organic materials.|Corrosives, Reactive - 3rd degree

|Danger|H271: May cause fire or explosion; strong Oxidizer [Danger Oxidizing liquids; Oxidizing solids]|P210, P220, P221, P260, P264, P270, P271, P280, P283, P284, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P306+P360, P307+P311, P309+P311, P310, P314, P320, P321, P331, P363, P370+P378, P371+P380+P375, P403+P233, P405, and P501

Excerpt from ERG Guide 144 [Oxidizers (Water-Reactive)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 1745 datasheet. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 144 [Oxidizers (Water-Reactive)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. DO NOT GET WATER on spilled substance or inside containers. SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. LARGE SPILL: DO NOT CLEAN-UP OR DISPOSE OF, EXCEPT UNDER SUPERVISION OF A SPECIALIST. (ERG, 2016)

Skin: Wear appropriate personal protective clothing to prevent skin contact. Eyes: Wear appropriate eye protection to prevent eye contact. Wash skin: The worker should immediately wash the skin when it becomes contaminated. Remove: Work clothing that becomes wet or significantly contaminated should be removed and replaced. Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. Provide: Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substance; this is irrespective of the recommendation involving the wearing of eye protection. Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2016)|Wear appropriate personal protective clothing to prevent skin contact.|Wear appropriate eye protection to prevent eye contact.|Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substance; this is irrespective of the recommendation involving the wearing of eye protection.|Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. (Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.)|... Positive pressure self-contained breathing apparatus.|(See protection codes)

... Not combustible ...

If material involved in fire: Do not use water on material itself. Use dry chemical or carbon dioxide. Cool all affected containers with flooding quantities of water. If large quantities of combustibles are involved, use water in flooding quantities as spray and fog. Use water spray to knock-down vapors.|Evacuation: If fire becomes uncontrollable or container is exposed to direct flame-consider evacuation of one-third (1/3) mile radius. If material leaking (not on fire) consider evacuation form downwind area based on amount of material spilled, location and weather conditions.|... Use appropriate extinguishing agents on nearby fires. Use dry chemical, dry sand, or carbon dioxide. Use water spray to keep fire-exposed containers cool.

/Bromine pentafluoride/ contacts with water causes a violent reaction or explosion, oxygen being evolved.

Isolate the area until the release is under full control. Use water spray to cool and disperse vapors and protect personnel.

SRP: Contaminated protective clothing should be segregated in a manner such that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.|If material not involved in fire: Do not use water itself. Keep material out of water sources and sewers. Use water spray to knock-down vapors. Neutralize spilled material with crushed limestone, soda ash, or lime.|Personnel protection: Avoid breathing vapors. Keep upwind. ... Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriated personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.|The worker should immediately wash the skin when it becomes contaminated.|Work clothing that becomes wet or significantly contaminated should be removed and replaced.

If ... THERE IS NO FIRE, go directly to the Table of Initial Isolation and Protective Action Distances /(see table below)/ ... to obtain initial isolation and protective action distances. IF THERE IS A FIRE, or IF A FIRE IS INVOLVED, go directly to the appropriate guide /(see guide(s) below)/ and use the evacuation information shown under PUBLIC SAFETY.|Table of Water-Reactive Materials Which Produce Toxic Gases.|/GUIDE 144 OXIDIZERS (Water-Reactive)/ Fire or Explosion: May ignite combustibles (wood, paper, oil, clothing, etc.). React vigorously and/or explosively with water. Produce toxic and/or corrosive substances on contact with water. Flammable/toxic gases may accumulate in tanks and hopper cars. Some may produce flammable hydrogen gas upon contact with metals. Containers may explode when heated. Runoff may create fire or explosion hazard.|For more DOT Emergency Guidelines (Complete) data for BROMINE PENTAFLUORIDE (11 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials. Bromine pentafluoride is included on the dangerous goods list.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article. Bromine pentafluoride is included on the dangerous goods list.

... Corrosive. Causes severe eye and skin burns. Irritating to skin, eyes, and respiratory system.|BrF5 provides adequate warning of its presence by its sharp, penetrating odor.

Recommended Exposure Limit: 10 Hour Time-Weighted Average: 0.1 ppm (0.7 mg/cu m).

Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in vermiculite, earth, dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Do NOT absorb in saw-dust or other combustible absorbents. NEVER direct water jet on liquid.

Separated from food and feedstuffs and all other substances. See Chemical Dangers. Dry. Well closed. Keep in a well-ventilated room.

A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.

The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. Exposure could cause death.

May cause fluorosis due to formation of hydrogen fluoride. Further see ICSC 0283.

NO contact with flammables. NO contact with water, combustible substances or organic materials.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!

Use closed system or ventilation.

Protective gloves. Protective clothing.

Wear safety goggles or eye protection in combination with breathing protection.

| 4 - Materials that, under emergency conditions, can be lethal.| 0 - Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand.| 3 - Materials that in themselves are capable of detonation or explosive decomposition or explosive reaction but that require a strong initiating source or must be heated under confinement before initiation.|OX - Oxidizer: Materials that possess oxidizing properties.

IDENTIFICATION AND USE: Bromine pentafluoride (BrF5) is a liquid with a sharp penetrating odor. BrF5 is predominantly used as a fluorinating agent to produce fluorocarbons and as an oxidizer in rocket propellant systems. Metal chlorides, bromides, and iodides are converted to fluorides by treatment with BrF5. Uranium is converted to uranium hexafluoride by strong oxidizing agents, including BrF5. HUMAN EXPOSURE AND TOXICITY: Acute exposure to BrF5 can cause redness and tearing of the eyes, coughing, breathing difficulty, and a burning sensation of the eyes, nose, and throat. Direct contact of this substance with the eyes or skin can cause severe thermal and chemical burns and tissue destruction. The acute effect of this substance on the lung is similar to that of phosgene. Individuals with asthma may respond to exposure to respiratory irritants with increased bronchial responsiveness. The elderly and those who are ill may also have increased susceptibility to the effects of irritants. Individuals under stress, such as those involved in emergency situations and individuals engaged in physical activity, will experience greater deposition and pulmonary irritation than individuals at rest. Furthermore, individuals who breathe through their mouths would be at greater risk. ANIMAL STUDIES: BrF5 has been shown to be acutely toxic in animals. Animals exposed to bromine pentafluoride vapor at 500 ppm exhibited immediate symptoms of gasping, swollen eyelids, clouded corneas, tearing, salivation, and acute distress; these symptoms appeared after exposure for a period as short as three minutes. Exposures to 50 ppm were fatal after 30 minutes, and chronic exposures above 3 ppm resulted in severe nephrosis (in some animals), as well as marked hepatosis and severe respiratory involvement.

Individuals with asthma may respond to exposure to respiratory irritants with increased bronchial responsiveness. The elderly and those who are ill may also have increased susceptibility to the effects of irritants. Individuals under stress, such as those involved in emergency situations and individuals engaged in physical activity, will experience greater deposition and pulmonary irritation than individuals at rest. Furthermore, individuals who breathe through their mouths would be at greater risk.

Bromine pentafluoride's production and use as a fluorinating agent in uranium processing and as the oxidizer component of some rocket propellants(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Bromine pentafluoride decomposes, sometimes explosively, on contact with water(1) and hydrogen-containing materials(2).|AQUATIC FATE: Bromine pentafluoride decomposes, sometimes explosively, on contact with water to yield hydrofluoric acid and other materials(1).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), bromine pentafluoride, which has a vapor pressure of 406 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Bromine pentafluoride is a relatively heavy vapor with a vapor density 6.05 times that of air(3). Bromine pentafluoride explodes and decomposes on contact with water to yield hydrofluoric acid and other materials(4). It fumes in air(5), reacts with steam, and decomposes on contact with hydrogen-containing materials(3).

Bromine pentafluoride decomposes, sometimes explosively, on contact with water to yield hydrofluoric acid and other materials(1). It also explodes or ignites on contact with hydrogen-containing materials (e.g. acetic acid, ammonia, benzene, ethanol, hydrogen, hydrogen sulfide, methane cork, grease, paper, wax)(2).

Bromine pentafluoride decomposes, sometimes explosively, on contact with water to yield hydrofluoric acid and other materials(1). Therefore, bioconcentration in fish is not expected to be an important fate process(SRC).

Bromine pentafluoride decomposes, sometimes explosively, on contact with water(1). It also explodes or ignites on contact with hydrogen-containing materials (e.g. acetic acid, ammonia, benzene, ethanol, hydrogen, hydrogen sulfide, methane cork, grease, paper, wax)(2).

Bromine pentafluoride decomposes, sometimes explosively, on contact with water to yield hydrofluoric acid and other materials(1). Therefore, volatilization from water is not expected to be an important fate process(SRC).

Occupational exposure to bromine pentafluoride may occur through inhalation and dermal contact with this compound at workplaces where bromine pentafluoride is produced or used. (SRC)

/Investigators/ measured fluoride in rat tissues following exposure to BrF5 at 500 ppm for 30 min or ClF3 at 400 ppm for 15 min... The data show increased fluoride content in the blood and lungs immediately after exposure, which declined over time. Mean fluoride in bone increased from 300 ug/g immediately after exposure to BrF5 to 353 ug/g 20 hr later. After exposure to ClF3, mean fluoride in bone increased from 118 to 172 ug/g over a 24-hr period. Although a small number of animals (four to six) are represented by the mean values and fluoride concentrations in untreated rats varied widely, the data suggest that, at higher concentrations of halogen fluorides, fluoride may be absorbed into the bloodstream and distributed to bone and other tissues.

...the halogen fluorides are expected to hydrolyze rapidly in the moist respiratory tract. /Halogen fluorides/

The mechanism by which halogen fluorides exert their acute toxicity is by direct irritation and corrosion. In experimental animals, these strong oxidizing chemicals produce lacrimation, sneezing, and salivation, which progresses to nausea, difficult respiration, and unconsciousness with cyanosis. Lacrimation and rhinorrhea are responses to stimulation of the trigeminal nerve. The eyes and exposed skin suffer burns. At the high concentrations that cause lethality, the capacity of the upper respiratory tract to scrub the halogen fluorides from the inhaled air is exceeded, and the chemicals penetrate to the lungs, causing edema and destruction of the pulmonary tissue. These signs were observed in monkeys, dogs, rats, and mice exposed to ClF5 and in rats exposed to BrF5.

Chemical is highly corrosive and toxic. Inhalation causes severe burns of mucous membrane. Ingestion causes severe burns of mouth. Contact with eyes or skin causes severe burns. (USCG, 1999)

Eye: If this chemical contacts the eyes, immediately wash the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Contact lenses should not be worn when working with this chemical. Skin: If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly. Breathing: If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform mouth-to-mouth resuscitation. Keep the affected person warm and at rest. Get medical attention as soon as possible. Swallow: If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2016)|(See procedures)

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Keep unconscious victims warm and on their sides to avoid choking if vomiting occurs. Immediately initiate the following emergency procedures, continuing them as appropriate en route to the emergency medical facility. 1. Eye Exposure: Tissue destruction and blindness may result from exposure to concentrated solutions, vapors, mists or aerosols of bromine pentafluoride! Immediately but gently flush the eyes with large amounts of water for at least 15 min, occasionally lifting the upper and lower eyelids. 2. Skin exposure: Severe burns, skin corrosion, and absorption of toxic amounts may result! Immediately remove all contaminated clothing! Immediately and gently wash skin for at least 15 min. Use soap and water if skin is intact; use only water if skin is not intact. 3. Inhalation exposure: If vapors, mists, or aerosols of bromine pentafluoride are inhaled, move the victim to fresh air immediately. If the victim is not breathing, clean any chemical contamination from the victim's lips and perform cardiopulmonary resuscitation; if breathing is difficult, give oxygen. 4. Ingestion exposure: Take the following steps if several pentafluoride or a solution containing it is ingested: Do not induce vomiting. Have the victim rinse the contaminated mouth cavity several times with a fluid such as water. Immediately after rinsing, have the victim drink one cup (8 ox) of fluid and no more. Do not permit the victim to drink milk or carbonated beverages! Do not permit the victim to drink any fluid if more than 60 min have passed since initial ingestion.|Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Bromine, methyl bromide, and related compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with dry sterile dressings after decontamination ... . /Bromine, methyl bromide, and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Bromine, methyl bromide, and related compounds/

/SIGNS AND SYMPTOMS/ Acute exposure to bromine pentafluoride can cause redness and tearing of the eyes, coughing, breathing difficulty, and a burning sensation of the eyes, nose, and throat. Direct contact of this substance with the eyes or skin can cause severe thermal and chemical burns and tissue destruction.|/SIGNS AND SYMPTOMS/ Skin or eye contact with vapor or liquid bromine pentafluoride causes painful, deep-seated, long-lasting burns. ...|/OTHER TOXICITY INFORMATION/ ...use of BrF5 and BrF3 in the synthesis of uranium hexafluoride suggests the possibility of coexposure to bromine and uranium fluorides in the context of accidental releases. As HF is a hydrolysis product of both the bromine fluorides and uranium hexafluoride, coexposure to these compounds might lead to greater toxicity due to higher levels of the reaction product HF.

The substance can be absorbed into the body by inhalation of its vapour.|inhalation, ingestion, skin and/or eye contact

irritation eyes, skin, respiratory system; corneal necrosis; skin burns; cough, dyspnea (breathing difficulty), pulmonary edema; liver, kidney injury

Burning sensation. Cough. Shortness of breath. Sore throat. Laboured breathing. Symptoms may be delayed.

Redness. Pain. Skin burns. Blisters.

Redness. Pain. Blurred vision. Severe deep burns.

Eyes, skin, respiratory system, liver, kidneys

Fire Hazards -> Corrosives, Reactive - 3rd degree