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Home > Encyclopedia > Octadecanoic acid, 12-hydroxy-, polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl)

Octadecanoic acid, 12-hydroxy-, polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl)

pharmaceutical raw materials
Octadecanoic acid, 12-hydroxy-, polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) structure

Octadecanoic acid, 12-hydroxy-, polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) 

structure
  • CAS No:

    70142-34-6

  • Formula:

    (C18H36O3.(C2H4O)nH2O)x

  • Chemical Name:

    Octadecanoic acid, 12-hydroxy-, polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl)

  • Synonyms:

    Octadecanoic acid,12-hydroxy-,polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl);Poly(oxy-1,2-ethanediyl),α-hydro-ω-hydroxy-,polymer with 12-hydroxyoctadecanoic acid

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Polyoxyl 15 hydroxystearate is a nonionic surfactant and emulsifier. Polyoxyl 15 hydroxystearate is used for improving the solubility and dissolution of poorly watersoluble drugs[1][2].

Octadecanoic acid, 12-hydroxy-, polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) Basic Attributes

963.23800

962.63900

DTXSID9052769

3907990100

Characteristics

216.21000

4.13460

521.6 °F

Macrogol 15 hydroxystearate has a high chemical stability. The prolonged action of heat may induce physical separation into a liquid and a solid phase after cooling, which can be reversed by subsequent homogenization. Macrogol 15 hydroxystearate is stable for at least 24 months if stored in unopened airtight containers at room temperature (maximum 25 °C). Aqueous solutions of macrogol 15 hydroxystearate can be heat-sterilized (121°C, 0.21 MPa). The pH may drop slightly during heating, which sho

Safety Information

NONH for all modes of transport

3

24-37

Xi

P280

H317

|Warning|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501|Aggregated GHS information provided by 201 companies from 2 notifications to the ECHA C&L Inventory.

Octadecanoic acid, 12-hydroxy-, polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl) Use and Manufacturing

Uses

Non-ionic surfactant.

EPA Safer Chemical Functional Use Classes -> Polymers|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Computed Properties

Molecular Weight:949.2
XLogP3:1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:60
Exact Mass:948.62328070
Monoisotopic Mass:948.62328070
Topological Polar Surface Area:216
Heavy Atom Count:65
Complexity:881
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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